Río Sereno Vacations
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Río Sereno Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
MARINN Tropical Vibes Hotel
Amador
Price was $1,424, price is now $1,118 per person
$1,118
per person
Dec 18 - Dec 26
found 1 day ago
Roundtrip non-stop flight included
Cincinnati (CVG) to Panama City (PTY)
Stay at this 3.5-star hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.
Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $3,142, price is now $1,914 per person
$1,914
per person
Dec 18 - Dec 26
found 1 day ago
Roundtrip non-stop flight included
Cincinnati (CVG) to Panama City (PTY)
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Hotel Riu Plaza Panama
Bella Vista
Price was $1,851, price is now $1,350 per person
$1,350
per person
Dec 18 - Dec 26
found 1 day ago
Roundtrip non-stop flight included
Cincinnati (CVG) to Panama City (PTY)
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Bristol Panama, a Registry Collection Hotel
Bella Vista
Price was $2,327, price is now $1,729 per person
$1,729
per person
Dec 18 - Dec 26
found 1 day ago
Roundtrip non-stop flight included
Cincinnati (CVG) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Megapolis Hotel Panamá
San Francisco
Price was $1,848, price is now $1,401 per person
$1,401
per person
Dec 18 - Dec 26
found 1 day ago
Roundtrip non-stop flight included
Cincinnati (CVG) to Panama City (PTY)
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Las Americas Golden Tower Panama
San Francisco
Price was $1,899, price is now $1,447 per person
$1,447
per person
Dec 18 - Dec 26
found 1 day ago
Roundtrip non-stop flight included
Cincinnati (CVG) to Panama City (PTY)
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Top Hotel Deals
Hotel Bambito By Faranda Boutique, a member of Radisson Individuals
Volcan, Via Cerro Punta, Volcan, Chiriqui
23.02 km from city center
Stay at this 3-star family-friendly hotel in Volcan. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Área Silvestre Protegida Lagunas ...
Hotel Finca Lerida
Alto Quiel, Los Naranjos, Chiriqui
40.11 km from city center
Stay at this 3-star hotel in Los Naranjos. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Finca Lérida Coffee Estate and Los Ladrillos ...
Casa Grande Bambito Resort
Calle El Manantial, Paso Ancho, Chiriqui
24.26 km from city center
Stay at this 4-star family-friendly hotel in Paso Ancho. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Área Silvestre Protegida ...
Los Brezos Boutique Hotel
Calle Tercera Norte, Volcan, Chiriquí
22.79 km from city center
Stay at this 3.5-star business-friendly hotel in Volcan. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Área Silvestre Protegida Lagunas ...
Hotel Dos Rios
43, Nueva California, Nueva California
20.04 km from city center
Stay at this 3-star hotel in Nueva California. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Área Silvestre Protegida Lagunas de Volcán ...
Risco de Hugo
2 Volcancito Road, Boquete, Chiriquí Province
39.46 km from city center
Stay at this cabin in Boquete. Enjoy free WiFi, free parking, and furnished balconies. Popular attractions Finca Lérida Coffee Estate and Los Ladrillos are located ...
Los Quetzales Ecolodge & Spa
Guadalupe, Cerro Punta, Chiriqui
30.21 km from city center
Stay at this 3-star spa lodge in Cerro Punta. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Finca Dracula Orchid Sanctuary and The ...
Hostal Victoria Volcán Chiriquí S. A.
Volcan Chiriquí, Calle Estudiante Calle 3era y Calle 4ta, Nueva California, Chiriquí
21.77 km from city center
Stay at this hostal in Nueva California. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Área Silvestre Protegida Lagunas de Volcán ...
Hotel Las Canarias
Carretera puerto armuelles, Paso Canoas, Provincia de Chiriquí
32.16 km from city center
Stay at this 3-star hotel in Paso Canoas. Enjoy free WiFi, free parking, and 4 restaurants.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Tue, Dec 2 - Sun, Dec 7
ORD
O'Hare Intl.
DAV
Enrique Malek Intl.
$779 Roundtrip, found 2 days ago
$779
Roundtrip
found 2 days ago
Mon, Jan 19 - Fri, Feb 6
ORD
O'Hare Intl.
DAV
Enrique Malek Intl.
$794 Roundtrip, found 2 days ago
$794
Roundtrip
found 2 days ago
Thu, Feb 19 - Mon, Mar 9
ORD
O'Hare Intl.
DAV
Enrique Malek Intl.
$807 Roundtrip, found 2 days ago
$807
Roundtrip
found 2 days ago
Thu, Nov 20 - Wed, Dec 3
ORD
O'Hare Intl.
DAV
Enrique Malek Intl.
$1,255 Roundtrip, found 2 days ago
$1,255
Roundtrip
found 2 days ago