Eastern Panama Vacation Packages for 2025
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Eastern Panama Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
MARINN Tropical Vibes Hotel
Amador
Price was $834, price is now $623 per person
$623
per person
Nov 27 - Dec 2
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Stay at this 3.5-star hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.
Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $1,783, price is now $1,068 per person
$1,068
per person
Nov 27 - Dec 2
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Hotel Riu Plaza Panama
Bella Vista
Price was $1,071, price is now $764 per person
$764
per person
Nov 27 - Dec 2
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Mahogany Suites
Price was $957, price is now $707 per person
$707
per person
Nov 27 - Dec 2
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Stay at this hotel in Arraijan. Enjoy free WiFi and an outdoor pool. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.
Bristol Panama, a Registry Collection Hotel
Bella Vista
Price was $1,346, price is now $1,011 per person
$1,011
per person
Nov 27 - Dec 2
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Dreams Playa Bonita Panama - All Inclusive
Price was $1,638, price is now $1,244 per person
$1,244
per person
Nov 27 - Dec 2
found 1 day ago
Roundtrip non-stop flight included
Baltimore (BWI) to Panama City (PTY)
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.
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See all available trips from Columbus to Eastern Panama
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Ordovician Beach Resort
Isla Grande, Isla Grande, Colon
160.42 km from city center
Stay at this 4.5-star luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National ...
Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island, Narganá, Guna Yala
92.59 km from city center
Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attractions Isla Diablo and Isla Chichime ...
San Blas Paradise Private Cabins on Shipwreck Island - meals included
Perro Island, Narganá, Guna Yala
92.17 km from city center
Book a stay at this beach hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Diablo ...
Ciel y Miel
Caillle Principale, Cacique, Provincia de Colón
164.99 km from city center
Stay at this 3-star beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park ...
Hotel Cocotal
La Guaira, Isla Grande, Provincia de Colón
160.23 km from city center
Stay at this hotel in Isla Grande. Enjoy free breakfast, free WiFi, and 20 restaurants. Popular attractions Isla Mamey and Portobelo National Park are located ...
Konsenda San Blas
Llano Cartí Km 11, El Llano, Panamá Province
86.7 km from city center
Stay at this hotel in El Llano. Enjoy free breakfast, free parking, and a garden.
Ranchos de Chalia
Portobelo via Puerto Lindo, Unit 3, Puerto Lindo, Colón
161.23 km from city center
Stay at this 3-star hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are ...
Private Over the Water Cabin on San Blas Island
9.542876, -78.899058, Narganá, San Blas
93 km from city center
Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Chichime ...
Cabins in Asserya Island - San Blas paradise - meals included
Aroma Island (Isla Anzuelo), Narganá, Guna Yala
91.98 km from city center
Stay at this hotel in San Blas Islands. Enjoy free breakfast, a marina, and an airport shuttle (surcharge). Popular attractions Museum and Isla Chichime are ...
Discovery Gunayar
Archipiélago de San Blas, Narganá, Guna Yala
86.38 km from city center
Book a stay at this beach lodge in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Chichime and Isla ...
Private bedroom on paradise San Blas Island - Meals Included
Isla Yansailadup, Narganá, Guna Yala
91.86 km from city center
Stay at this guesthouse in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Diablo and Museum of the ...
Paradise Over the Water Cabins in San Blas
G4V2 48, Narganá, Guna Yala
98.35 km from city center
Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Porvenir Museum ...
San Blas Tour Aridub
Urgandi, Guna Yala, Panamá, Narganá, Guna Yala
80.42 km from city center
Book a stay at this beach cabin in Narganá. Enjoy beach cabanas (surcharge), a beach shuttle (surcharge), and daily housekeeping.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Wed, Dec 24 - Wed, Dec 31
MIA
Miami Intl.
PTY
Tocumen Intl.
$377 Roundtrip, found 5 days ago
$377
Roundtrip
found 5 days ago
Sat, Dec 27 - Sat, Jan 3
MIA
Miami Intl.
PTY
Tocumen Intl.
$511 Roundtrip, found 5 days ago
$511
Roundtrip
found 5 days ago
Sat, Dec 27 - Sat, Jan 3
MIA
Miami Intl.
PTY
Tocumen Intl.
$649 Roundtrip, found 5 days ago
$649
Roundtrip
found 5 days ago
Sat, Dec 27 - Sat, Jan 3
MIA
Miami Intl.
PTY
Tocumen Intl.
$1,119 Roundtrip, found 5 days ago
$1,119
Roundtrip
found 5 days ago
Sat, Dec 27 - Sat, Jan 3
MIA
Miami Intl.
PTY
Tocumen Intl.
$1,548 Roundtrip, found 5 days ago
$1,548
Roundtrip
found 5 days ago