Vacations Close To Mayo Clinic
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Mayo Clinic Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
AmericInn by Wyndham Rochester Near Mayo Clinic
Price was $746, price is now $702 per person
$702
per person
Dec 7 - Dec 11
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTW) to Rochester (RST)
the shuttle to the mayo was great however you have to plan for at least 1 hr for the return trip. The down fall is that so many people in Rochester going to the mayo may be in a wheelchair, like myself and a very rare amount of shuttles form hotels are handicap accessible. This hotel work because I did not join my husband.
Reviewed on Oct 14, 2026
The Berkman
Folwell
Price was $1,055, price is now $944 per person
$944
per person
Dec 7 - Dec 11
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTW) to Rochester (RST)
Room was awesome! We had the 3 bedroom unit, which had a large and spacious balcony. Plenty of sunlight came through those windows. We couldn’t had had a better room!
Reviewed on Oct 9, 2026
The Wen Inn formerly Andor Wenneson
Price was $894, price is now $835 per person
$835
per person
Dec 7 - Dec 11
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTW) to Rochester (RST)
Beautiful property and amazing host. This was the perfect location right on the trail. Breakfast was lovely!
Reviewed on Oct 11, 2026
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Historic Southwest
Price was $851, price is now $799 per person
$799
per person
Dec 7 - Dec 11
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTW) to Rochester (RST)
Convenient and clean which were my two biggest needs. Shuttle was awesome and kept us from trying to find parking. 2nd stay here so obviously we are happy with it.
Reviewed on Oct 14, 2026
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View all tripsBest Lodging Options Near Mayo Clinic
Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
0.12 km from Mayo Clinic
Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw Rochester MN
1.57 km from Mayo Clinic
Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
401 6th St Sw Rochester MN
0.61 km from Mayo Clinic
Book a stay at this golf hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. ...
Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
0.2 km from Mayo Clinic
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S Rochester MN
2.58 km from Mayo Clinic
Book a stay at this spa hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful staff in our ...
Brentwood Inn & Suites
123 Fourth Ave. NW Rochester MN
0.31 km from Mayo Clinic
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the breakfast and the ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.