
Cheap 2026 Main South Hotels
Choose from 345 Main South Hotel Deals

Wellsworth Hotel
14 Mechanic St Southbridge MA
Free Cancellation
Reserve now, pay when you stay
25.89 km from Main South
Book a stay at this business-friendly hotel in Southbridge. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the pool and the helpful staff ...

DoubleTree by Hilton Hotel Boston - Westborough
5400 Computer Dr Westborough MA
Free Cancellation
Reserve now, pay when you stay
20.81 km from Main South
Book a stay at this business-friendly hotel in Westborough. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...

Embassy Suites by Hilton Boston Marlborough
123 Boston Post Rd W Marlborough MA
Free Cancellation
Reserve now, pay when you stay
21.57 km from Main South
Book a stay at this business-friendly hotel in Marlborough. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

Sonesta Select Boston Milford
10 Fortune Blvd Milford MA
Free Cancellation
Reserve now, pay when you stay
27.51 km from Main South
Book a stay at this business-friendly hotel in Milford. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...

Courtyard by Marriott Boston Marlborough
75 Felton St Marlborough MA
Free Cancellation
Reserve now, pay when you stay
22.4 km from Main South
Book a stay at this business-friendly hotel in Marlborough. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...

Motel 6 Framingham, MA - Boston West
1668 Worcester Rd Framingham MA
28.27 km from Main South
Stay at this motel in Framingham. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...

Hyatt Place Marlborough/Apex Center
169 Apex Drive Marlborough MA
Free Cancellation
Reserve now, pay when you stay
21.09 km from Main South
Book a stay at this business-friendly hotel in Marlborough. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

Hilton Garden Inn Worcester
35 Major Taylor Boulevard Worcester MA
Free Cancellation
Reserve now, pay when you stay
2.52 km from Main South
Book a stay at this business-friendly hotel in Worcester. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...

Red Roof Inn Boston - Southborough/ Worcester
367 Turnpike Rd Southborough MA
Free Cancellation
Reserve now, pay when you stay
21.81 km from Main South
Stay at this hotel in Southborough. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...

AC Hotel by Marriott Worcester
125 Front St Worcester MA
Free Cancellation
Reserve now, pay when you stay
2.09 km from Main South
Book a stay at this business-friendly hotel in Worcester. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...

Comfort Inn Auburn - Worcester
426 Southbridge St Auburn MA
5.72 km from Main South
Book a stay at this business-friendly hotel in Auburn. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...

Holiday Inn Express Boston - Milford by IHG
50 Fortune Blvd Milford MA
Free Cancellation
Reserve now, pay when you stay
27.89 km from Main South
Book a stay at this business-friendly hotel in Milford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Publick House Historic Inn and Country Motor Lodge
277 Main Street (RT 131) Sturbridge MA
Free Cancellation
Reserve now, pay when you stay
26.67 km from Main South
Book a stay at this spa resort in Sturbridge. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the helpful staff and the clean ...

Courtyard by Marriott Worcester
72 Grove Street Worcester MA
Free Cancellation
Reserve now, pay when you stay
3.07 km from Main South
Book a stay at this business-friendly hotel in Worcester. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...

Hampton Inn & Suites Worcester
65 Prescott St Worcester MA
Free Cancellation
Reserve now, pay when you stay
3.17 km from Main South
Book a stay at this business-friendly hotel in Worcester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Main South, Worcester Hotel Guide
Search for hotels in Main South on Expedia.com. You can easily find your hotels in Main South using one of the methods below:
- View our selection of featured hotels in Main South
- Use the map to find hotels in the Main South neighborhood you prefer
- Use the filters to see hotels in a specific area of Main South, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Main South
- Enter your travel dates to view the best deals on hotels in Main South - while they last
