Downtown Vacation Packages for 2025

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Top Hotel Deals

Quality Inn Seneca US-123

Quality Inn Seneca US-123

2.5 out of 5
226 Hi Tech Rd, Seneca, SC
0.59 km from Downtown
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd, Clemson, SC
11.78 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St, Clemson, SC
10.61 km from Downtown
Stay at this 4-star hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and valet parking (surcharge). Our guests praise the helpful staff and the clean ...
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd, Seneca, SC
8.58 km from Downtown
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Inn @ Clemson

Inn @ Clemson

2.5 out of 5
1303 Tiger Blvd, Clemson, SC
11.64 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd, Anderson, SC
25.64 km from Downtown
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd, Clemson, SC
11.67 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
12.41 km from Downtown
Stay at this 3-star cottage in Clemson. Enjoy free parking and air conditioning. Popular attractions Clemson Area African American Museum and Larry W. Abernathy ...
Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

2 out of 5
102 Electric City Blvd, Anderson, SC
24.8 km from Downtown
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Postcard Cabins Lake Hartwell

Postcard Cabins Lake Hartwell

2 out of 5
299 Outpost Rd, Seneca, SC
7.49 km from Downtown
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG

2.5 out of 5
1381 Tiger Blvd, Clemson, SC
12.42 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

2.5 out of 5
107 Interstate Blvd, Anderson, SC
24.97 km from Downtown
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
The Inn at Patrick Square

The Inn at Patrick Square

3.5 out of 5
115 Market Street, Clemson, SC
15.23 km from Downtown
Stay at this 3.5-star hotel in Clemson. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd, Seneca, SC
8.33 km from Downtown
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
The Abernathy of Clemson

The Abernathy of Clemson

4 out of 5
157 Old Greenville Hwy, Clemson, SC
10.1 km from Downtown
Stay at this 4-star business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Jul 5 - Tue, Jul 8
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$189 Roundtrip, found 5 days ago
$189
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Jul 5 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Tue, Jul 8, priced at $189 found 5 days ago
Delta
Thu, Jul 3 - Thu, Jul 10
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$209 Roundtrip, found 5 days ago
$209
Roundtrip
found 5 days ago
Select Delta flight, departing Thu, Jul 3 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Thu, Jul 10, priced at $209 found 5 days ago
Delta
Wed, May 14 - Wed, May 21
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$219 Roundtrip, found 1 day ago
$219
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, May 14 from LaGuardia to Greenville-Spartanburg Intl., returning Wed, May 21, priced at $219 found 1 day ago
American Airlines
Sat, Oct 18 - Tue, Oct 21
PHL
Philadelphia Intl.
GSP
Greenville-Spartanburg Intl.
$371 Roundtrip, found 4 days ago
$371
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Oct 18 from Philadelphia Intl. to Greenville-Spartanburg Intl., returning Tue, Oct 21, priced at $371 found 4 days ago