Downtown Vacation Packages for 2026

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Top Hotel Deals

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
0.59 km from Downtown
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd Anderson SC
25.64 km from Downtown
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
Clemson SC
12.41 km from Downtown
Stay at this cottage in Clemson. Enjoy air conditioning. Popular attractions Clemson Area African American Museum and Larry W. Abernathy Waterfront Park are ...
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
11.78 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
10.61 km from Downtown
Stay at this hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
11.67 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
Hilton Garden Inn Anderson

Hilton Garden Inn Anderson

3 out of 5
115 Destination Blvd Anderson SC
25.66 km from Downtown
Book a stay at this business-friendly hotel in Anderson. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

2 out of 5
102 Electric City Blvd Anderson SC
24.8 km from Downtown
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
8.58 km from Downtown
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Inn @ Clemson

Inn @ Clemson

2.5 out of 5
1303 Tiger Blvd Clemson SC
11.64 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

2.5 out of 5
128 Interstate Blvd Anderson SC
25.02 km from Downtown
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd Seneca SC
8.33 km from Downtown
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Quality Inn Clemson near University

Quality Inn Clemson near University

2.5 out of 5
3430 Clemson Blvd Anderson SC
29.59 km from Downtown
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
The Inn at Patrick Square

The Inn at Patrick Square

3.5 out of 5
115 Market Street Clemson SC
15.23 km from Downtown
Stay at this hotel in Clemson. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Hampton Inn & Suites Lavonia

Hampton Inn & Suites Lavonia

2.5 out of 5
115 Owens Drive Lavonia GA
30.72 km from Downtown
Book a stay at this business-friendly hotel in Lavonia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Jan 10 - Tue, Jan 13
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$152 Roundtrip, found 1 day ago
$152
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Jan 10 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Tue, Jan 13, priced at $152 found 1 day ago
Delta
Sat, Jan 10 - Tue, Jan 13
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$162 Roundtrip, found 1 day ago
$162
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Jan 10 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Tue, Jan 13, priced at $162 found 1 day ago
United
Wed, Jan 21 - Mon, Jan 26
EWR
Newark Liberty Intl. Airport
GSP
Greenville-Spartanburg Intl.
$209 Roundtrip, found 15 hours ago
$209
Roundtrip
found 15 hours ago
Select United flight, departing Wed, Jan 21 from Newark Liberty Intl. Airport to Greenville-Spartanburg Intl., returning Mon, Jan 26, priced at $209 found 15 hours ago
Southwest Airlines
Mon, Dec 22 - Thu, Dec 25
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$527 Roundtrip, found 1 day ago
$527
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Mon, Dec 22 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Thu, Dec 25, priced at $527 found 1 day ago