Downtown Vacation Packages for 2026

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Top Hotel Deals

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd Anderson SC
25.64 km from Downtown
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
11.78 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2 out of 5
299 Outpost Rd Seneca SC
7.54 km from Downtown
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreation Area and Cross Creek Plantation Golf ...
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

3 out of 5
240 Madren Center Drive Clemson SC
10.3 km from Downtown
Book a stay at this golf hotel in Clemson. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our ...
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
8.58 km from Downtown
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Inn @ Clemson

Inn @ Clemson

2.5 out of 5
1303 Tiger Blvd Clemson SC
11.64 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Quality Inn Seneca US-123

Quality Inn Seneca US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
3.8 km from Downtown
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
11.67 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
The Abernathy of Clemson

The Abernathy of Clemson

4 out of 5
157 Old Greenville Hwy Clemson SC
10.1 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
10.61 km from Downtown
Stay at this hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Woodspring Suites Anderson North I-85

Woodspring Suites Anderson North I-85

2.5 out of 5
155 Threlkeld Boulevard Anderson SC
25.37 km from Downtown
Stay at this hotel in Anderson. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions Regal Starlight - Anderson and Anderson Civic ...
Courtyard Marriott Clemson

Courtyard Marriott Clemson

3 out of 5
201 Canoy Ln Clemson SC
12.9 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Popular attractions Memorial Stadium and ...
The Inn at Patrick Square

The Inn at Patrick Square

3.5 out of 5
115 Market Street Clemson SC
15.23 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and ...
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd Seneca SC
8.42 km from Downtown
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street Seneca SC
2.18 km from Downtown
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Nov 19 - Sat, Nov 21
EWR
Newark Liberty Intl. Airport
GSP
Greenville-Spartanburg Intl.
$359 Roundtrip, found 1 day ago
$359
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Nov 19 from Newark Liberty Intl. Airport to Greenville-Spartanburg Intl., returning Sat, Nov 21, priced at $359 found 1 day ago
United
Mon, Nov 16 - Tue, Nov 24
EWR
Newark Liberty Intl. Airport
GSP
Greenville-Spartanburg Intl.
$359 Roundtrip, found 1 day ago
$359
Roundtrip
found 1 day ago
Select United flight, departing Mon, Nov 16 from Newark Liberty Intl. Airport to Greenville-Spartanburg Intl., returning Tue, Nov 24, priced at $359 found 1 day ago
American Airlines
Wed, Nov 18 - Tue, Dec 22
EWR
Newark Liberty Intl. Airport
GSP
Greenville-Spartanburg Intl.
$379 Roundtrip, found 2 days ago
$379
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Nov 18 from Newark Liberty Intl. Airport to Greenville-Spartanburg Intl., returning Tue, Dec 22, priced at $379 found 2 days ago
Southwest Airlines
Fri, Nov 13 - Sat, Nov 14
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$459 Roundtrip, found 2 days ago
$459
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Fri, Nov 13 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Nov 14, priced at $459 found 2 days ago