Downtown Vacation Packages for 2026

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Top Hotel Deals

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
0.59 km from Downtown
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
11.78 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
10.61 km from Downtown
Stay at this hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2 out of 5
299 Outpost Rd Seneca SC
7.54 km from Downtown
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
8.58 km from Downtown
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Inn @ Clemson

Inn @ Clemson

2.5 out of 5
1303 Tiger Blvd Clemson SC
11.64 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd Anderson SC
25.64 km from Downtown
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

3 out of 5
240 Madren Center Drive Clemson SC
10.3 km from Downtown
Book a stay at this golf hotel in Clemson. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our ...
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
11.67 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
The Inn at Patrick Square

The Inn at Patrick Square

3.5 out of 5
115 Market Street Clemson SC
15.23 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and ...
Quality Inn Clemson near University

Quality Inn Clemson near University

2.5 out of 5
3430 Clemson Blvd Anderson SC
29.59 km from Downtown
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street Seneca SC
2.18 km from Downtown
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
The Abernathy of Clemson

The Abernathy of Clemson

4 out of 5
157 Old Greenville Hwy Clemson SC
10.1 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
Woodspring Suites Anderson North I-85

Woodspring Suites Anderson North I-85

2.5 out of 5
155 Threlkeld Boulevard Anderson SC
25.37 km from Downtown
Stay at this hotel in Anderson. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions Regal Starlight - Anderson and Anderson Civic ...
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd Seneca SC
8.42 km from Downtown
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Apr 16 - Mon, May 4
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$211 Roundtrip, found 1 day ago
$211
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Apr 16 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Mon, May 4, priced at $211 found 1 day ago
American Airlines
Mon, Apr 13 - Fri, May 1
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$213 Roundtrip, found 1 day ago
$213
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Apr 13 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Fri, May 1, priced at $213 found 1 day ago
Southwest Airlines
Fri, Apr 10 - Sat, Apr 11
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$255 Roundtrip, found 1 day ago
$255
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Fri, Apr 10 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Sat, Apr 11, priced at $255 found 1 day ago
United
Fri, Jun 12 - Sun, Jun 14
EWR
Newark Liberty Intl. Airport
GSP
Greenville-Spartanburg Intl.
$259 Roundtrip, found 2 days ago
$259
Roundtrip
found 2 days ago
Select United flight, departing Fri, Jun 12 from Newark Liberty Intl. Airport to Greenville-Spartanburg Intl., returning Sun, Jun 14, priced at $259 found 2 days ago