Downtown Vacation Packages for 2026

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Top Hotel Deals

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
0.59 km from Downtown
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd Anderson SC
25.64 km from Downtown
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
10.61 km from Downtown
Stay at this hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
11.78 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
8.58 km from Downtown
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Inn @ Clemson

Inn @ Clemson

2.5 out of 5
1303 Tiger Blvd Clemson SC
11.64 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
11.67 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Woodspring Suites Anderson North I-85

Woodspring Suites Anderson North I-85

2.5 out of 5
155 Threlkeld Boulevard Anderson SC
25.37 km from Downtown
Stay at this hotel in Anderson. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions Regal Starlight - Anderson and Anderson Civic ...
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

3 out of 5
240 Madren Center Drive Clemson SC
10.3 km from Downtown
Book a stay at this golf hotel in Clemson. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our ...
Courtyard Marriott Clemson

Courtyard Marriott Clemson

3 out of 5
201 Canoy Ln Clemson SC
12.9 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Memorial Stadium and Clemson ...
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2 out of 5
299 Outpost Rd Seneca SC
7.54 km from Downtown
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

3 out of 5
800 BYPASS 123 Seneca SC
2.01 km from Downtown
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
The Inn at Patrick Square

The Inn at Patrick Square

3.5 out of 5
115 Market Street Clemson SC
15.23 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and ...
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

2.5 out of 5
107 Interstate Blvd Anderson SC
25.02 km from Downtown
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
The Abernathy of Clemson

The Abernathy of Clemson

4 out of 5
157 Old Greenville Hwy Clemson SC
10.1 km from Downtown
Book a stay at this business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Jul 21 - Tue, Jul 28
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$157 Roundtrip, found 13 hours ago
$157
Roundtrip
found 13 hours ago
Select Delta flight, departing Tue, Jul 21 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Tue, Jul 28, priced at $157 found 13 hours ago
American Airlines
Tue, Jul 21 - Tue, Jul 28
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$248 Roundtrip, found 13 hours ago
$248
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Tue, Jul 21 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Tue, Jul 28, priced at $248 found 13 hours ago
Southwest Airlines
Tue, Jul 21 - Tue, Jul 28
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$269 Roundtrip, found 13 hours ago
$269
Roundtrip
found 13 hours ago
Select Southwest Airlines flight, departing Tue, Jul 21 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Tue, Jul 28, priced at $269 found 13 hours ago
United
Tue, Jun 30 - Sat, Jul 4
ORD
O'Hare Intl.
GSP
Greenville-Spartanburg Intl.
$275 Roundtrip, found 17 hours ago
$275
Roundtrip
found 17 hours ago
Select United flight, departing Tue, Jun 30 from O'Hare Intl. to Greenville-Spartanburg Intl., returning Sat, Jul 4, priced at $275 found 17 hours ago