Adults Only Resorts & Hotels in South Carolina
Check availability on South Carolina Adults Only Resorts & Hotels
Pick from 42 South Carolina Adults Only Resorts & Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
86 Cannon Charleston - Adults Only
Downtown Charleston
10.0 out of 10, Exceptional, (72)
"The perfect place to stay if your visiting Charleston "
Stephanie
Affordable Suites Myrtle Beach
Myrtle Beach
8.6 out of 10, Excellent, (289)
"Good place to stay"
edyta
Baymont by Wyndham Orangeburg North
Orangeburg
6.0 out of 10, (1007)
"Very clean and quiet "
Niquisha
The Jasmine House
Charleston Historic District
9.2 out of 10, Wonderful, (364)
"Great Stay, Great Location, Great Staff"
Sam
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top South Carolina Hotel Reviews
Explore a world of travel with Expedia
Top destinations for Adults Only Resorts & Hotels in South Carolina
More Hotel Options in South Carolina
- Hotels with Air Conditioning in South Carolina
- Hotels with WiFi in South Carolina
- Hotel with wifi in South Carolina
- Hotels with a Pool in South Carolina
- Hotels with Balconies in South Carolina
- Family Hotels in South Carolina
- Smoke Free Hotels in South Carolina
- Beach Hotels in South Carolina
- Hotels with Complimentary Breakfast in South Carolina
- Hotels with Hot Tubs in South Carolina
- Hotels with an Indoor Pool in South Carolina
- Pet-friendly Hotels in South Carolina
- Resorts & Hotels with Spas in South Carolina
- Hotels with Bars in South Carolina
- Cheap Hotels in South Carolina
More Themes
- Hotels with Air Conditioning
- All-inclusive Hotel
- Hotels with Balconies
- Hotels with Bars
- Beach Hotels
- Boutique Hotels
- Cheap Hotels
- Business Hotels
- Casinos
- Hotel with a Concierge
- Hotels with Restaurants
- Family Hotels
- Hotels with Fireplaces
- Hotels with a Fitness Center
- Hotels with Free Airport Shuttle
- Hotels with Complimentary Breakfast
- Hotels with Free Parking
- Hotel with wifi
- Golf Hotels
- Historic Hotels
- Hotels with Hot Tubs
- Hotels with an Indoor Pool
- Apartment Hotel
- Hotels with a Kitchen
- Lakefront Hotels
- Hotels with a Lazy River
- Gay friendly Hotels
- Luxury Hotels
- Smoke Free Hotels
- Oceanfront Hotels
- Pet-friendly Hotels
- Hotels with a Pool
- Adventure Hotels
- Hotels on the River
- Romantic Hotels
- Hotels with Room Service
- Secluded Hotels
- Shopping Hotels
- Ski Hotels
- Hotels with smoking rooms
- Resorts & Hotels with Spas
- Hotels with Suites
- Green Hotels
- Hotels with Tennis Courts
- Waterpark Hotels
- Hotels with Waterslides
- Hotel Wedding Venues
- Hotels with WiFi
- Winery Hotels
Other Accommodation Types in South Carolina
Stay near popular South Carolina attractions
- Hotels near Myrtle Beach Boardwalk
- Hotels near Fort Jackson
- Hotels near University of South Carolina
- Hotels near Broadway at the Beach
- Hotels near Carowinds Theme Park
- Hotels near Marine Corps Recruit Depot Parris Island
- Hotels near Clemson University
- Hotels near Port of Charleston
- Hotels near SkyWheel Myrtle Beach
- Hotels near College of Charleston
Discover hotels close to South Carolina with room rates, reviews, and availability. Most hotels are fully refundable.
- Emeline
- Hilton Greenville
- The Francis Marion Hotel
- Sea Crest Oceanfront Resort
- La Quinta Inn & Suites by Wyndham Myrtle Beach - N Kings Hwy
- The Ryder Hotel
- Holiday Inn Express Hilton Head Island by IHG
- Hilton Grand Vacations Club Ocean Enclave Myrtle Beach
- Anderson Ocean Club and Spa by Oceana Resorts
- Tru by Hilton Charleston Airport