2025 5 Star Hotels in Puerto Santa Ana

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Featured Puerto Santa Ana 5 Star Hotels

Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Oro Verde Guayaquil
Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel

5 out of 5
Av. Constitucion, Plaza del Sol, Frente al Mall del Sol, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Sheraton Guayaquil Hotel
Radisson Hotel Guayaquil

Radisson Hotel Guayaquil

5 out of 5
Avenida Gral Francisco Bolona 503A, y Calle Jorge Insua Hindr, Guayaquil, Pichincha
Radisson Hotel Guayaquil
The Royalty Inn

The Royalty Inn

5 out of 5
Ciudadela Simón Bolivar mz 8 villa 19, 4° Pt. 2A N-E y Av. Hermano Miguel, Guayaquil
Fully refundableReserve now, pay when you stay
The Royalty Inn
See all 388 properties in Puerto Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.