2026 5 Star Hotels in Isle of Palms

Choose two or more items and save on your trip:

Featured Isle of Palms 5 Star Hotels

The Gemma by Brightwild

The Gemma by Brightwild

5 out of 5
19 somerset Clearwater Beach FL
The Gemma by Brightwild
Little Harbor Resort at Bahia Beach

Little Harbor Resort at Bahia Beach

5 out of 5
557 Bahia Beach Blvd Ruskin FL
Little Harbor Resort at Bahia Beach
Indian Rocks Escape

Indian Rocks Escape

5 out of 5
10767 Danielle Dr Largo FL
Indian Rocks Escape
Sand Castle

Sand Castle

5 out of 5
717 N Shore Dr Anna Maria FL
Sand Castle
Amazing views on Treasure Island

Amazing views on Treasure Island

5 out of 5
125 110th Ave Treasure Island FL
Amazing views on Treasure Island
See all 16,013 properties in Isle of Palms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.