2026 5 Star Hotels in Irene

Choose two or more items and save on your trip:

Featured Irene 5 Star Hotels

Davinci Hotel And Suites On Nelson Mandela Square

Davinci Hotel And Suites On Nelson Mandela Square

5 out of 5
2 Maude Street, Corner of 5th Street Sandton Gauteng
Fully refundableReserve now, pay when you stay
Davinci Hotel And Suites On Nelson Mandela Square
NH Johannesburg Sandton Hotel

NH Johannesburg Sandton Hotel

5 out of 5
138 Rivonia Road Johannesburg Gauteng
Fully refundableReserve now, pay when you stay
NH Johannesburg Sandton Hotel
InterContinental Johannesburg O.R Tambo Airport by IHG

InterContinental Johannesburg O.R Tambo Airport by IHG

5 out of 5
Opposite Int'l Arrivals Hall Kempton Park Gauteng
Fully refundable
InterContinental Johannesburg O.R Tambo Airport by IHG
CT Hotel

CT Hotel

5 out of 5
643 Cnr Stanza Bopape & Wessels Street Pretoria Gauteng
Fully refundableReserve now, pay when you stay
CT Hotel
Palazzo Hotel

Palazzo Hotel

5 out of 5
Montecasino Boulevard Sandton Gauteng
Fully refundableReserve now, pay when you stay
Palazzo Hotel
The Capital on the Park

The Capital on the Park

5 out of 5
101 Katherine Street, Sandown Sandton Gauteng
Fully refundableReserve now, pay when you stay
The Capital on the Park
The Michelangelo Towers

The Michelangelo Towers

5 out of 5
8 Maud Street Sandown Sandton Gauteng
Fully refundableReserve now, pay when you stay
The Michelangelo Towers
The Capital Menlyn Maine

The Capital Menlyn Maine

5 out of 5
194 Bancor Avenue Pretoria Gauteng
Fully refundableReserve now, pay when you stay
The Capital Menlyn Maine
The Leonardo

The Leonardo

5 out of 5
75 Maude Street Sandton Gauteng
Fully refundableReserve now, pay when you stay
The Leonardo
See all 2,109 properties in Irene
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.