2025 4 Star Hotels in Texas Medical Center

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Featured Texas Medical Center 4 Star Hotels

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street, Houston, TX
Fully refundableReserve now, pay when you stay
Hotel Zaza Houston Museum District
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street, Houston, TX
Club Quarters Hotel Downtown, Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd, Houston, TX
Fully refundableReserve now, pay when you stay
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria

4 out of 5
2626 Sage Road, Houston, TX
Fully refundableReserve now, pay when you stay
Hyatt Regency Houston/Galleria
DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza

4 out of 5
Houston
Fully refundableReserve now, pay when you stay
DoubleTree by Hilton Hotel Houston - Greenway Plaza
The Westin Galleria Houston

The Westin Galleria Houston

4.5 out of 5
5060 W Alabama St, Houston, TX
Fully refundableReserve now, pay when you stay
The Westin Galleria Houston
C. Baldwin, Curio Collection by Hilton

C. Baldwin, Curio Collection by Hilton

4 out of 5
400 Dallas St, Houston, TX
Fully refundableReserve now, pay when you stay
C. Baldwin, Curio Collection by Hilton
The Whitehall Houston

The Whitehall Houston

4 out of 5
1700 Smith St, Houston, TX
Fully refundableReserve now, pay when you stay
The Whitehall Houston
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
Hilton Houston Plaza/Medical Center
See all 6,486 properties in Texas Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.