2026 4 Star Hotels in Santo Spirito

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Featured Santo Spirito 4 Star Hotels

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
Fully refundableReserve now, pay when you stay
Hotel Horto Convento
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
Palazzo Mannaioni Suites
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
Fully refundableReserve now, pay when you stay
UNA Hotels Vittoria Firenze
Torre di Bellosguardo

Torre di Bellosguardo

4 out of 5
Via Roti Michelozzi 2 Florence FI
Torre di Bellosguardo
See all 495 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.