2026 4 Star Hotels in Downtown San Diego

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Featured Downtown San Diego 4 Star Hotels

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
Hard Rock Hotel San Diego
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
Fully refundableReserve now, pay when you stay
Manchester Grand Hyatt San Diego
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Wyndham San Diego Bayside
San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter

4 out of 5
660 K St San Diego CA
Fully refundableReserve now, pay when you stay
San Diego Marriott Gaslamp Quarter
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

4 out of 5
675 L St San Diego CA
Fully refundableReserve now, pay when you stay
Omni San Diego Hotel at the Ballpark
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4 out of 5
333 W Harbor Dr San Diego CA
Fully refundableReserve now, pay when you stay
Marriott Marquis San Diego Marina
The Westin San Diego Bayview

The Westin San Diego Bayview

4 out of 5
1051 Columbia street San Diego CA
Fully refundableReserve now, pay when you stay
The Westin San Diego Bayview
Hotel Indigo San Diego-Gaslamp Quarter by IHG

Hotel Indigo San Diego-Gaslamp Quarter by IHG

4 out of 5
509 9th Ave San Diego CA
Fully refundable
Hotel Indigo San Diego-Gaslamp Quarter by IHG
Sentral Gaslamp Quarter

Sentral Gaslamp Quarter

4 out of 5
502 10th Avenue San Diego CA
Fully refundableReserve now, pay when you stay
Sentral Gaslamp Quarter
See all 832 properties in Downtown San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.