Flights from Des Moines to San Diego

Cheapest flights from Des Moines

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Jun 9 - Mon, Jun 16

DSM

Des Moines Intl.

SAN

San Diego Intl.

$232 Roundtrip, found 2 days ago

$232

Roundtrip

found 2 days ago

Select Frontier Airlines flight, departing Mon, Jun 9 from Des Moines Intl. to San Diego Intl., returning Mon, Jun 16, priced at $232 found 2 days ago

Mon, Jun 9 - Fri, Jun 20

DSM

Des Moines Intl.

SAN

San Diego Intl.

$251 Roundtrip, found 2 days ago

$251

Roundtrip

found 2 days ago

Select Frontier Airlines flight, departing Mon, Jun 9 from Des Moines Intl. to San Diego Intl., returning Fri, Jun 20, priced at $251 found 2 days ago

Fri, Jun 6 - Sun, Jun 15

DSM

Des Moines Intl.

SAN

San Diego Intl.

$252 Roundtrip, found 2 days ago

$252

Roundtrip

found 2 days ago

Select Frontier Airlines flight, departing Fri, Jun 6 from Des Moines Intl. to San Diego Intl., returning Sun, Jun 15, priced at $252 found 2 days ago

Fri, Jun 6 - Fri, Jun 13

DSM

Des Moines Intl.

SAN

San Diego Intl.

$272 Roundtrip, found 2 days ago

$272

Roundtrip

found 2 days ago

Select Frontier Airlines flight, departing Fri, Jun 6 from Des Moines Intl. to San Diego Intl., returning Fri, Jun 13, priced at $272 found 2 days ago

Tue, Jul 15 - Sat, Jul 26

DSM

Des Moines Intl.

SAN

San Diego Intl.

$321 Roundtrip, found 1 day ago

$321

Roundtrip

found 1 day ago

Select Delta flight, departing Tue, Jul 15 from Des Moines Intl. to San Diego Intl., returning Sat, Jul 26, priced at $321 found 1 day ago

Mon, Jul 21 - Fri, Jul 25

DSM

Des Moines Intl.

SAN

San Diego Intl.

$340 Roundtrip, found 1 day ago

$340

Roundtrip

found 1 day ago

Select Frontier Airlines flight, departing Mon, Jul 21 from Des Moines Intl. to San Diego Intl., returning Fri, Jul 25, priced at $340 found 1 day ago

Fri, Jun 6 - Fri, Jun 13

DSM

Des Moines Intl.

SAN

San Diego Intl.

$342 Roundtrip, found 4 days ago

$342

Roundtrip

found 4 days ago

Select Frontier Airlines flight, departing Fri, Jun 6 from Des Moines Intl. to San Diego Intl., returning Fri, Jun 13, priced at $342 found 4 days ago

Fri, Jul 18 - Mon, Jul 21

DSM

Des Moines Intl.

SAN

San Diego Intl.

$350 Roundtrip, found 1 day ago

$350

Roundtrip

found 1 day ago

Select Frontier Airlines flight, departing Fri, Jul 18 from Des Moines Intl. to San Diego Intl., returning Mon, Jul 21, priced at $350 found 1 day ago

Sat, Jul 19 - Sat, Jul 26

DSM

Des Moines Intl.

SAN

San Diego Intl.

$360 Roundtrip, found 1 day ago

$360

Roundtrip

found 1 day ago

Select Delta flight, departing Sat, Jul 19 from Des Moines Intl. to San Diego Intl., returning Sat, Jul 26, priced at $360 found 1 day ago

Tue, Jul 15 - Fri, Jul 25

DSM

Des Moines Intl.

SAN

San Diego Intl.

$364 Roundtrip, found 1 day ago

$364

Roundtrip

found 1 day ago

Select Delta flight, departing Tue, Jul 15 from Des Moines Intl. to San Diego Intl., returning Fri, Jul 25, priced at $364 found 1 day ago

Tue, Jun 10 - Mon, Jun 16

DSM

Des Moines Intl.

SAN

San Diego Intl.

$375 Roundtrip, found 2 days ago

$375

Roundtrip

found 2 days ago

Select Delta flight, departing Tue, Jun 10 from Des Moines Intl. to San Diego Intl., returning Mon, Jun 16, priced at $375 found 2 days ago

Tue, Jun 10 - Mon, Jun 16

DSM

Des Moines Intl.

SAN

San Diego Intl.

$380 Roundtrip, found 2 days ago

$380

Roundtrip

found 2 days ago

Select United flight, departing Tue, Jun 10 from Des Moines Intl. to San Diego Intl., returning Mon, Jun 16, priced at $380 found 2 days ago

Fri, Jul 18 - Fri, Jul 25

DSM

Des Moines Intl.

SAN

San Diego Intl.

$390 Roundtrip, found 1 day ago

$390

Roundtrip

found 1 day ago

Select Frontier Airlines flight, departing Fri, Jul 18 from Des Moines Intl. to San Diego Intl., returning Fri, Jul 25, priced at $390 found 1 day ago

Mon, Jun 9 - Mon, Jun 16

DSM

Des Moines Intl.

SAN

San Diego Intl.

$402 Roundtrip, found 2 days ago

$402

Roundtrip

found 2 days ago

Select Frontier Airlines flight, departing Mon, Jun 9 from Des Moines Intl. to San Diego Intl., returning Mon, Jun 16, priced at $402 found 2 days ago

Thu, Jul 17 - Fri, Jul 25

DSM

Des Moines Intl.

SAN

San Diego Intl.

$407 Roundtrip, found 1 day ago

$407

Roundtrip

found 1 day ago

Select Delta flight, departing Thu, Jul 17 from Des Moines Intl. to San Diego Intl., returning Fri, Jul 25, priced at $407 found 1 day ago

Tue, Jun 10 - Mon, Jun 16

DSM

Des Moines Intl.

SAN

San Diego Intl.

$412 Roundtrip, found 2 days ago

$412

Roundtrip

found 2 days ago

Select United flight, departing Tue, Jun 10 from Des Moines Intl. to San Diego Intl., returning Mon, Jun 16, priced at $412 found 2 days ago

Sun, Jul 20 - Tue, Jul 22

DSM

Des Moines Intl.

SAN

San Diego Intl.

$444 Roundtrip, found 1 day ago

$444

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sun, Jul 20 from Des Moines Intl. to San Diego Intl., returning Tue, Jul 22, priced at $444 found 1 day ago

Tue, Jun 10 - Tue, Jun 17

DSM

Des Moines Intl.

SAN

San Diego Intl.

$477 Roundtrip, found 2 days ago

$477

Roundtrip

found 2 days ago

Select United flight, departing Tue, Jun 10 from Des Moines Intl. to San Diego Intl., returning Tue, Jun 17, priced at $477 found 2 days ago

Tue, Jun 10 - Tue, Jun 17

DSM

Des Moines Intl.

CLD

McClellan-Palomar

$541 Roundtrip, found 2 days ago

$541

Roundtrip

found 2 days ago

Select American Airlines flight, departing Tue, Jun 10 from Des Moines Intl. to McClellan-Palomar, returning Tue, Jun 17, priced at $541 found 2 days ago

Tue, Jun 10 - Tue, Jun 17

DSM

Des Moines Intl.

SAN

San Diego Intl.

$623 Roundtrip, found 2 days ago

$623

Roundtrip

found 2 days ago

Select Alaska Airlines flight, departing Tue, Jun 10 from Des Moines Intl. to San Diego Intl., returning Tue, Jun 17, priced at $623 found 2 days ago