Flights from Des Moines to San Francisco

Cheapest flights from Des Moines

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Aug 28 - Sat, Sep 6

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$289 Roundtrip, found 6 days ago

$289

Roundtrip

found 6 days ago

Select Frontier Airlines flight, departing Thu, Aug 28 from Des Moines Intl. to San Francisco Intl., returning Sat, Sep 6, priced at $289 found 6 days ago

Thu, Aug 28 - Mon, Sep 8

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$294 Roundtrip, found 6 days ago

$294

Roundtrip

found 6 days ago

Select Frontier Airlines flight, departing Thu, Aug 28 from Des Moines Intl. to San Francisco Intl., returning Mon, Sep 8, priced at $294 found 6 days ago

Thu, Aug 28 - Fri, Sep 5

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$299 Roundtrip, found 6 days ago

$299

Roundtrip

found 6 days ago

Select Frontier Airlines flight, departing Thu, Aug 28 from Des Moines Intl. to San Francisco Intl., returning Fri, Sep 5, priced at $299 found 6 days ago

Fri, Aug 22 - Sun, Sep 7

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$304 Roundtrip, found 6 days ago

$304

Roundtrip

found 6 days ago

Select Frontier Airlines flight, departing Fri, Aug 22 from Des Moines Intl. to San Francisco Intl., returning Sun, Sep 7, priced at $304 found 6 days ago

Fri, Aug 29 - Sat, Sep 6

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$304 Roundtrip, found 6 days ago

$304

Roundtrip

found 6 days ago

Select Frontier Airlines flight, departing Fri, Aug 29 from Des Moines Intl. to San Francisco Intl., returning Sat, Sep 6, priced at $304 found 6 days ago

Sun, Sep 7 - Sun, Sep 14

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$326 Roundtrip, found 1 day ago

$326

Roundtrip

found 1 day ago

Select Frontier Airlines flight, departing Sun, Sep 7 from Des Moines Intl. to San Francisco Intl., returning Sun, Sep 14, priced at $326 found 1 day ago

Wed, Sep 10 - Sat, Sep 13

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$333 Roundtrip, found 1 day ago

$333

Roundtrip

found 1 day ago

Select Delta flight, departing Wed, Sep 10 from Des Moines Intl. to San Francisco Intl., returning Sat, Sep 13, priced at $333 found 1 day ago

Fri, Aug 29 - Sat, Sep 6

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$348 Roundtrip, found 6 days ago

$348

Roundtrip

found 6 days ago

Select Frontier Airlines flight, departing Fri, Aug 29 from Des Moines Intl. to San Francisco Intl., returning Sat, Sep 6, priced at $348 found 6 days ago

Wed, Sep 10 - Sun, Sep 14

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$357 Roundtrip, found 1 day ago

$357

Roundtrip

found 1 day ago

Select Delta flight, departing Wed, Sep 10 from Des Moines Intl. to San Francisco Intl., returning Sun, Sep 14, priced at $357 found 1 day ago

Thu, Aug 28 - Tue, Sep 2

DSM

Des Moines Intl.

OAK

Oakland Intl.

$367 Roundtrip, found 5 days ago

$367

Roundtrip

found 5 days ago

Select Delta flight, departing Thu, Aug 28 from Des Moines Intl. to Oakland Intl., returning Tue, Sep 2, priced at $367 found 5 days ago

Fri, Aug 29 - Sat, Sep 6

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$380 Roundtrip, found 6 days ago

$380

Roundtrip

found 6 days ago

Select American Airlines flight, departing Fri, Aug 29 from Des Moines Intl. to San Francisco Intl., returning Sat, Sep 6, priced at $380 found 6 days ago

Fri, Aug 29 - Sat, Sep 6

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$381 Roundtrip, found 6 days ago

$381

Roundtrip

found 6 days ago

Select Delta flight, departing Fri, Aug 29 from Des Moines Intl. to San Francisco Intl., returning Sat, Sep 6, priced at $381 found 6 days ago

Thu, Aug 28 - Sat, Aug 30

DSM

Des Moines Intl.

OAK

Oakland Intl.

$382 Roundtrip, found 5 days ago

$382

Roundtrip

found 5 days ago

Select Delta flight, departing Thu, Aug 28 from Des Moines Intl. to Oakland Intl., returning Sat, Aug 30, priced at $382 found 5 days ago

Fri, Aug 29 - Sat, Sep 6

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$398 Roundtrip, found 6 days ago

$398

Roundtrip

found 6 days ago

Select United flight, departing Fri, Aug 29 from Des Moines Intl. to San Francisco Intl., returning Sat, Sep 6, priced at $398 found 6 days ago

Fri, Aug 29 - Sat, Sep 6

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$400 Roundtrip, found 6 days ago

$400

Roundtrip

found 6 days ago

Select United flight, departing Fri, Aug 29 from Des Moines Intl. to San Francisco Intl., returning Sat, Sep 6, priced at $400 found 6 days ago

Fri, Aug 29 - Sat, Sep 6

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$402 Roundtrip, found 6 days ago

$402

Roundtrip

found 6 days ago

Select American Airlines flight, departing Fri, Aug 29 from Des Moines Intl. to San Francisco Intl., returning Sat, Sep 6, priced at $402 found 6 days ago

Tue, Aug 26 - Tue, Sep 2

DSM

Des Moines Intl.

OAK

Oakland Intl.

$403 Roundtrip, found 5 days ago

$403

Roundtrip

found 5 days ago

Select Delta flight, departing Tue, Aug 26 from Des Moines Intl. to Oakland Intl., returning Tue, Sep 2, priced at $403 found 5 days ago

Fri, Aug 29 - Sat, Sep 6

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$406 Roundtrip, found 6 days ago

$406

Roundtrip

found 6 days ago

Select American Airlines flight, departing Fri, Aug 29 from Des Moines Intl. to San Francisco Intl., returning Sat, Sep 6, priced at $406 found 6 days ago

Fri, Aug 29 - Sat, Sep 6

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$407 Roundtrip, found 6 days ago

$407

Roundtrip

found 6 days ago

Select United flight, departing Fri, Aug 29 from Des Moines Intl. to San Francisco Intl., returning Sat, Sep 6, priced at $407 found 6 days ago

Fri, Aug 29 - Sat, Sep 6

DSM

Des Moines Intl.

SFO

San Francisco Intl.

$410 Roundtrip, found 6 days ago

$410

Roundtrip

found 6 days ago

Select Delta flight, departing Fri, Aug 29 from Des Moines Intl. to San Francisco Intl., returning Sat, Sep 6, priced at $410 found 6 days ago