Flights from Roanoke to Chicago

Cheapest flights from Roanoke

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Nov 17 - Sat, Nov 22

ROA

Roanoke Regional

ORD

O'Hare Intl.

$209 Roundtrip, found 5 days ago

$209

Roundtrip

found 5 days ago

Select United flight, departing Mon, Nov 17 from Roanoke Regional to O'Hare Intl., returning Sat, Nov 22, priced at $209 found 5 days ago

Mon, Nov 17 - Sat, Nov 22

ROA

Roanoke Regional

ORD

O'Hare Intl.

$219 Roundtrip, found 5 days ago

$219

Roundtrip

found 5 days ago

Select United flight, departing Mon, Nov 17 from Roanoke Regional to O'Hare Intl., returning Sat, Nov 22, priced at $219 found 5 days ago

Mon, Nov 17 - Sat, Nov 22

ROA

Roanoke Regional

ORD

O'Hare Intl.

$225 Roundtrip, found 5 days ago

$225

Roundtrip

found 5 days ago

Select United flight, departing Mon, Nov 17 from Roanoke Regional to O'Hare Intl., returning Sat, Nov 22, priced at $225 found 5 days ago

Tue, Dec 2 - Sat, Dec 6

ROA

Roanoke Regional

ORD

O'Hare Intl.

$229 Roundtrip, found 5 days ago

$229

Roundtrip

found 5 days ago

Select Delta flight, departing Tue, Dec 2 from Roanoke Regional to O'Hare Intl., returning Sat, Dec 6, priced at $229 found 5 days ago

Mon, Nov 17 - Sat, Nov 22

ROA

Roanoke Regional

ORD

O'Hare Intl.

$234 Roundtrip, found 5 days ago

$234

Roundtrip

found 5 days ago

Select United flight, departing Mon, Nov 17 from Roanoke Regional to O'Hare Intl., returning Sat, Nov 22, priced at $234 found 5 days ago

Mon, Dec 1 - Sat, Dec 6

ROA

Roanoke Regional

ORD

O'Hare Intl.

$235 Roundtrip, found 5 days ago

$235

Roundtrip

found 5 days ago

Select United flight, departing Mon, Dec 1 from Roanoke Regional to O'Hare Intl., returning Sat, Dec 6, priced at $235 found 5 days ago

Mon, Nov 17 - Sat, Nov 22

ROA

Roanoke Regional

ORD

O'Hare Intl.

$244 Roundtrip, found 5 days ago

$244

Roundtrip

found 5 days ago

Select American Airlines flight, departing Mon, Nov 17 from Roanoke Regional to O'Hare Intl., returning Sat, Nov 22, priced at $244 found 5 days ago

Tue, Nov 18 - Wed, Nov 19

ROA

Roanoke Regional

ORD

O'Hare Intl.

$251 Roundtrip, found 5 days ago

$251

Roundtrip

found 5 days ago

Select Delta flight, departing Tue, Nov 18 from Roanoke Regional to O'Hare Intl., returning Wed, Nov 19, priced at $251 found 5 days ago

Thu, Nov 13 - Tue, Nov 18

ROA

Roanoke Regional

ORD

O'Hare Intl.

$269 Roundtrip, found 5 days ago

$269

Roundtrip

found 5 days ago

Select Delta flight, departing Thu, Nov 13 from Roanoke Regional to O'Hare Intl., returning Tue, Nov 18, priced at $269 found 5 days ago

Tue, Jun 17 - Wed, Jun 25

ROA

Roanoke Regional

ORD

O'Hare Intl.

$279 Roundtrip, found 17 hours ago

$279

Roundtrip

found 17 hours ago

Select Delta flight, departing Tue, Jun 17 from Roanoke Regional to O'Hare Intl., returning Wed, Jun 25, priced at $279 found 17 hours ago

Mon, Nov 17 - Sat, Nov 22

ROA

Roanoke Regional

ORD

O'Hare Intl.

$279 Roundtrip, found 5 days ago

$279

Roundtrip

found 5 days ago

Select United flight, departing Mon, Nov 17 from Roanoke Regional to O'Hare Intl., returning Sat, Nov 22, priced at $279 found 5 days ago

Mon, Dec 1 - Sat, Dec 6

ROA

Roanoke Regional

ORD

O'Hare Intl.

$285 Roundtrip, found 5 days ago

$285

Roundtrip

found 5 days ago

Select United flight, departing Mon, Dec 1 from Roanoke Regional to O'Hare Intl., returning Sat, Dec 6, priced at $285 found 5 days ago

Mon, Nov 17 - Sat, Nov 22

ROA

Roanoke Regional

ORD

O'Hare Intl.

$289 Roundtrip, found 5 days ago

$289

Roundtrip

found 5 days ago

Select United flight, departing Mon, Nov 17 from Roanoke Regional to O'Hare Intl., returning Sat, Nov 22, priced at $289 found 5 days ago

Tue, Dec 2 - Sun, Dec 7

ROA

Roanoke Regional

ORD

O'Hare Intl.

$289 Roundtrip, found 5 days ago

$289

Roundtrip

found 5 days ago

Select United flight, departing Tue, Dec 2 from Roanoke Regional to O'Hare Intl., returning Sun, Dec 7, priced at $289 found 5 days ago

Mon, Nov 17 - Sat, Nov 22

ROA

Roanoke Regional

ORD

O'Hare Intl.

$291 Roundtrip, found 5 days ago

$291

Roundtrip

found 5 days ago

Select United flight, departing Mon, Nov 17 from Roanoke Regional to O'Hare Intl., returning Sat, Nov 22, priced at $291 found 5 days ago

Thu, Jul 3 - Sun, Jul 6

ROA

Roanoke Regional

ORD

O'Hare Intl.

$292 Roundtrip, found 17 hours ago

$292

Roundtrip

found 17 hours ago

Select United flight, departing Thu, Jul 3 from Roanoke Regional to O'Hare Intl., returning Sun, Jul 6, priced at $292 found 17 hours ago

Mon, Nov 17 - Sat, Nov 22

ROA

Roanoke Regional

ORD

O'Hare Intl.

$294 Roundtrip, found 5 days ago

$294

Roundtrip

found 5 days ago

Select United flight, departing Mon, Nov 17 from Roanoke Regional to O'Hare Intl., returning Sat, Nov 22, priced at $294 found 5 days ago

Mon, Dec 1 - Sat, Dec 6

ROA

Roanoke Regional

ORD

O'Hare Intl.

$295 Roundtrip, found 5 days ago

$295

Roundtrip

found 5 days ago

Select United flight, departing Mon, Dec 1 from Roanoke Regional to O'Hare Intl., returning Sat, Dec 6, priced at $295 found 5 days ago

Thu, Jul 3 - Sun, Jul 6

ROA

Roanoke Regional

ORD

O'Hare Intl.

$297 Roundtrip, found 17 hours ago

$297

Roundtrip

found 17 hours ago

Select United flight, departing Thu, Jul 3 from Roanoke Regional to O'Hare Intl., returning Sun, Jul 6, priced at $297 found 17 hours ago

Fri, Jul 4 - Mon, Jul 7

ROA

Roanoke Regional

MDW

Midway Intl.

$304 Roundtrip, found 17 hours ago

$304

Roundtrip

found 17 hours ago

Select Delta flight, departing Fri, Jul 4 from Roanoke Regional to Midway Intl., returning Mon, Jul 7, priced at $304 found 17 hours ago