Flights from Detroit to Santa Rosa

Cheapest flights from Detroit

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Oct 29 - Tue, Nov 11

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$259 Roundtrip, found 3 days ago

$259

Roundtrip

found 3 days ago

Select JetBlue Airways flight, departing Wed, Oct 29 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Tue, Nov 11, priced at $259 found 3 days ago

Wed, Oct 29 - Mon, Nov 10

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$276 Roundtrip, found 7 hours ago

$276

Roundtrip

found 7 hours ago

Select JetBlue Airways flight, departing Wed, Oct 29 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Nov 10, priced at $276 found 7 hours ago

Sun, Nov 2 - Sat, Nov 8

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$278 Roundtrip, found 3 days ago

$278

Roundtrip

found 3 days ago

Select Frontier Airlines flight, departing Sun, Nov 2 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Sat, Nov 8, priced at $278 found 3 days ago

Fri, Oct 31 - Sun, Nov 9

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$284 Roundtrip, found 3 days ago

$284

Roundtrip

found 3 days ago

Select Frontier Airlines flight, departing Fri, Oct 31 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Sun, Nov 9, priced at $284 found 3 days ago

Wed, Oct 29 - Mon, Nov 10

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$287 Roundtrip, found 7 hours ago

$287

Roundtrip

found 7 hours ago

Select American Airlines flight, departing Wed, Oct 29 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Nov 10, priced at $287 found 7 hours ago

Wed, Oct 29 - Mon, Nov 10

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$288 Roundtrip, found 7 hours ago

$288

Roundtrip

found 7 hours ago

Select American Airlines flight, departing Wed, Oct 29 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Nov 10, priced at $288 found 7 hours ago

Wed, Oct 29 - Mon, Nov 10

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$289 Roundtrip, found 7 hours ago

$289

Roundtrip

found 7 hours ago

Select JetBlue Airways flight, departing Wed, Oct 29 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Nov 10, priced at $289 found 7 hours ago

Wed, Oct 29 - Mon, Nov 10

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$289 Roundtrip, found 7 hours ago

$289

Roundtrip

found 7 hours ago

Select United flight, departing Wed, Oct 29 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Nov 10, priced at $289 found 7 hours ago

Wed, Oct 29 - Mon, Nov 10

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$293 Roundtrip, found 7 hours ago

$293

Roundtrip

found 7 hours ago

Select American Airlines flight, departing Wed, Oct 29 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Nov 10, priced at $293 found 7 hours ago

Fri, Oct 31 - Sun, Nov 9

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$295 Roundtrip, found 3 days ago

$295

Roundtrip

found 3 days ago

Select JetBlue Airways flight, departing Fri, Oct 31 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Sun, Nov 9, priced at $295 found 3 days ago

Wed, Oct 29 - Mon, Nov 10

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$296 Roundtrip, found 7 hours ago

$296

Roundtrip

found 7 hours ago

Select JetBlue Airways flight, departing Wed, Oct 29 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Nov 10, priced at $296 found 7 hours ago

Tue, Oct 28 - Sat, Nov 8

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$297 Roundtrip, found 3 days ago

$297

Roundtrip

found 3 days ago

Select Delta flight, departing Tue, Oct 28 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Sat, Nov 8, priced at $297 found 3 days ago

Wed, Oct 29 - Mon, Nov 10

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$298 Roundtrip, found 7 hours ago

$298

Roundtrip

found 7 hours ago

Select Alaska Airlines flight, departing Wed, Oct 29 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Nov 10, priced at $298 found 7 hours ago

Wed, Oct 29 - Mon, Nov 10

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$299 Roundtrip, found 7 hours ago

$299

Roundtrip

found 7 hours ago

Select United flight, departing Wed, Oct 29 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Nov 10, priced at $299 found 7 hours ago

Wed, Oct 29 - Mon, Nov 10

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$303 Roundtrip, found 7 hours ago

$303

Roundtrip

found 7 hours ago

Select American Airlines flight, departing Wed, Oct 29 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Nov 10, priced at $303 found 7 hours ago

Fri, Oct 31 - Sun, Nov 9

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$305 Roundtrip, found 3 days ago

$305

Roundtrip

found 3 days ago

Select American Airlines flight, departing Fri, Oct 31 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Sun, Nov 9, priced at $305 found 3 days ago

Wed, Oct 29 - Mon, Nov 10

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$306 Roundtrip, found 7 hours ago

$306

Roundtrip

found 7 hours ago

Select JetBlue Airways flight, departing Wed, Oct 29 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Nov 10, priced at $306 found 7 hours ago

Wed, Oct 29 - Mon, Nov 10

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$309 Roundtrip, found 7 hours ago

$309

Roundtrip

found 7 hours ago

Select United flight, departing Wed, Oct 29 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Nov 10, priced at $309 found 7 hours ago

Fri, Oct 31 - Sun, Nov 9

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$312 Roundtrip, found 3 days ago

$312

Roundtrip

found 3 days ago

Select Frontier Airlines flight, departing Fri, Oct 31 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Sun, Nov 9, priced at $312 found 3 days ago

Wed, Oct 29 - Mon, Nov 10

DTW

Detroit Metropolitan Wayne County

SFO

San Francisco Intl.

$462 Roundtrip, found 7 hours ago

$462

Roundtrip

found 7 hours ago

Select Alaska Airlines flight, departing Wed, Oct 29 from Detroit Metropolitan Wayne County to San Francisco Intl., returning Mon, Nov 10, priced at $462 found 7 hours ago