Flights from Chicago to La Mesa

Cheapest flights from Chicago

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Jun 25 - Mon, Jun 30

ORD

O'Hare Intl.

SAN

San Diego Intl.

$175 Roundtrip, found 8 hours ago

$175

Roundtrip

found 8 hours ago

Select Spirit Airlines flight, departing Wed, Jun 25 from O'Hare Intl. to San Diego Intl., returning Mon, Jun 30, priced at $175 found 8 hours ago

Thu, Jun 26 - Sat, Jun 28

ORD

O'Hare Intl.

SAN

San Diego Intl.

$176 Roundtrip, found 8 hours ago

$176

Roundtrip

found 8 hours ago

Select Spirit Airlines flight, departing Thu, Jun 26 from O'Hare Intl. to San Diego Intl., returning Sat, Jun 28, priced at $176 found 8 hours ago

Sat, Jun 28 - Mon, Jun 30

ORD

O'Hare Intl.

SAN

San Diego Intl.

$182 Roundtrip, found 8 hours ago

$182

Roundtrip

found 8 hours ago

Select Spirit Airlines flight, departing Sat, Jun 28 from O'Hare Intl. to San Diego Intl., returning Mon, Jun 30, priced at $182 found 8 hours ago

Sat, Jun 28 - Wed, Jul 2

ORD

O'Hare Intl.

SAN

San Diego Intl.

$189 Roundtrip, found 8 hours ago

$189

Roundtrip

found 8 hours ago

Select Spirit Airlines flight, departing Sat, Jun 28 from O'Hare Intl. to San Diego Intl., returning Wed, Jul 2, priced at $189 found 8 hours ago

Tue, Jun 24 - Wed, Jun 25

ORD

O'Hare Intl.

SAN

San Diego Intl.

$193 Roundtrip, found 8 hours ago

$193

Roundtrip

found 8 hours ago

Select Frontier Airlines flight, departing Tue, Jun 24 from O'Hare Intl. to San Diego Intl., returning Wed, Jun 25, priced at $193 found 8 hours ago

Wed, Jun 25 - Sat, Jun 28

ORD

O'Hare Intl.

SAN

San Diego Intl.

$194 Roundtrip, found 8 hours ago

$194

Roundtrip

found 8 hours ago

Select Spirit Airlines flight, departing Wed, Jun 25 from O'Hare Intl. to San Diego Intl., returning Sat, Jun 28, priced at $194 found 8 hours ago

Tue, Jun 24 - Mon, Jun 30

ORD

O'Hare Intl.

SAN

San Diego Intl.

$195 Roundtrip, found 8 hours ago

$195

Roundtrip

found 8 hours ago

Select Spirit Airlines flight, departing Tue, Jun 24 from O'Hare Intl. to San Diego Intl., returning Mon, Jun 30, priced at $195 found 8 hours ago

Thu, Jun 26 - Sat, Jun 28

ORD

O'Hare Intl.

SAN

San Diego Intl.

$196 Roundtrip, found 8 hours ago

$196

Roundtrip

found 8 hours ago

Select Spirit Airlines flight, departing Thu, Jun 26 from O'Hare Intl. to San Diego Intl., returning Sat, Jun 28, priced at $196 found 8 hours ago

Thu, Jun 26 - Sat, Jun 28

ORD

O'Hare Intl.

SAN

San Diego Intl.

$199 Roundtrip, found 8 hours ago

$199

Roundtrip

found 8 hours ago

Select Spirit Airlines flight, departing Thu, Jun 26 from O'Hare Intl. to San Diego Intl., returning Sat, Jun 28, priced at $199 found 8 hours ago

Tue, Jun 24 - Wed, Jul 2

ORD

O'Hare Intl.

SAN

San Diego Intl.

$202 Roundtrip, found 8 hours ago

$202

Roundtrip

found 8 hours ago

Select Spirit Airlines flight, departing Tue, Jun 24 from O'Hare Intl. to San Diego Intl., returning Wed, Jul 2, priced at $202 found 8 hours ago

Thu, Jun 26 - Sat, Jun 28

ORD

O'Hare Intl.

SAN

San Diego Intl.

$206 Roundtrip, found 8 hours ago

$206

Roundtrip

found 8 hours ago

Select Frontier Airlines flight, departing Thu, Jun 26 from O'Hare Intl. to San Diego Intl., returning Sat, Jun 28, priced at $206 found 8 hours ago

Sat, Jun 28 - Sun, Jun 29

ORD

O'Hare Intl.

SAN

San Diego Intl.

$209 Roundtrip, found 8 hours ago

$209

Roundtrip

found 8 hours ago

Select Spirit Airlines flight, departing Sat, Jun 28 from O'Hare Intl. to San Diego Intl., returning Sun, Jun 29, priced at $209 found 8 hours ago

Wed, Jun 25 - Thu, Jul 3

ORD

O'Hare Intl.

SAN

San Diego Intl.

$211 Roundtrip, found 8 hours ago

$211

Roundtrip

found 8 hours ago

Select Spirit Airlines flight, departing Wed, Jun 25 from O'Hare Intl. to San Diego Intl., returning Thu, Jul 3, priced at $211 found 8 hours ago

Sun, Oct 5 - Thu, Oct 16

ORD

O'Hare Intl.

SAN

San Diego Intl.

$237 Roundtrip, found 6 days ago

$237

Roundtrip

found 6 days ago

Select Hawaiian Airlines flight, departing Sun, Oct 5 from O'Hare Intl. to San Diego Intl., returning Thu, Oct 16, priced at $237 found 6 days ago

Tue, Oct 7 - Tue, Oct 14

ORD

O'Hare Intl.

SAN

San Diego Intl.

$237 Roundtrip, found 6 days ago

$237

Roundtrip

found 6 days ago

Select Alaska Airlines flight, departing Tue, Oct 7 from O'Hare Intl. to San Diego Intl., returning Tue, Oct 14, priced at $237 found 6 days ago

Tue, Oct 7 - Tue, Oct 14

ORD

O'Hare Intl.

SAN

San Diego Intl.

$237 Roundtrip, found 6 days ago

$237

Roundtrip

found 6 days ago

Select United flight, departing Tue, Oct 7 from O'Hare Intl. to San Diego Intl., returning Tue, Oct 14, priced at $237 found 6 days ago

Tue, Oct 7 - Tue, Oct 14

ORD

O'Hare Intl.

SAN

San Diego Intl.

$237 Roundtrip, found 6 days ago

$237

Roundtrip

found 6 days ago

Select American Airlines flight, departing Tue, Oct 7 from O'Hare Intl. to San Diego Intl., returning Tue, Oct 14, priced at $237 found 6 days ago

Tue, Oct 7 - Tue, Oct 14

ORD

O'Hare Intl.

SAN

San Diego Intl.

$257 Roundtrip, found 6 days ago

$257

Roundtrip

found 6 days ago

Select Delta flight, departing Tue, Oct 7 from O'Hare Intl. to San Diego Intl., returning Tue, Oct 14, priced at $257 found 6 days ago

Thu, Jun 26 - Sat, Jun 28

ORD

O'Hare Intl.

CLD

McClellan-Palomar

$297 Roundtrip, found 8 hours ago

$297

Roundtrip

found 8 hours ago

Select American Airlines flight, departing Thu, Jun 26 from O'Hare Intl. to McClellan-Palomar, returning Sat, Jun 28, priced at $297 found 8 hours ago

Tue, Oct 7 - Tue, Oct 14

ORD

O'Hare Intl.

SAN

San Diego Intl.

$403 Roundtrip, found 6 days ago

$403

Roundtrip

found 6 days ago

Select JetBlue Airways flight, departing Tue, Oct 7 from O'Hare Intl. to San Diego Intl., returning Tue, Oct 14, priced at $403 found 6 days ago