Flights from Chicago to Edisto Beach

Cheapest flights from Chicago

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$213 Roundtrip, found 3 hours ago

$213

Roundtrip

found 3 hours ago

Select Frontier Airlines flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $213 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$248 Roundtrip, found 3 hours ago

$248

Roundtrip

found 3 hours ago

Select United flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $248 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$258 Roundtrip, found 3 hours ago

$258

Roundtrip

found 3 hours ago

Select American Airlines flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $258 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$269 Roundtrip, found 3 hours ago

$269

Roundtrip

found 3 hours ago

Select JetBlue Airways flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $269 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$271 Roundtrip, found 3 hours ago

$271

Roundtrip

found 3 hours ago

Select United flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $271 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$271 Roundtrip, found 3 hours ago

$271

Roundtrip

found 3 hours ago

Select American Airlines flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $271 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$281 Roundtrip, found 3 hours ago

$281

Roundtrip

found 3 hours ago

Select American Airlines flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $281 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$283 Roundtrip, found 3 hours ago

$283

Roundtrip

found 3 hours ago

Select United flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $283 found 3 hours ago

Sat, Oct 11 - Wed, Oct 15

MDW

Midway Intl.

CHS

Charleston Intl.

$291 Roundtrip, found 3 hours ago

$291

Roundtrip

found 3 hours ago

Select Delta flight, departing Sat, Oct 11 from Midway Intl. to Charleston Intl., returning Wed, Oct 15, priced at $291 found 3 hours ago

Sun, Oct 12 - Mon, Oct 20

ORD

O'Hare Intl.

CHS

Charleston Intl.

$291 Roundtrip, found 3 hours ago

$291

Roundtrip

found 3 hours ago

Select Delta flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Mon, Oct 20, priced at $291 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$293 Roundtrip, found 3 hours ago

$293

Roundtrip

found 3 hours ago

Select American Airlines flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $293 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$297 Roundtrip, found 3 hours ago

$297

Roundtrip

found 3 hours ago

Select Delta flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $297 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$305 Roundtrip, found 3 hours ago

$305

Roundtrip

found 3 hours ago

Select United flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $305 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$307 Roundtrip, found 3 hours ago

$307

Roundtrip

found 3 hours ago

Select American Airlines flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $307 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$307 Roundtrip, found 3 hours ago

$307

Roundtrip

found 3 hours ago

Select JetBlue Airways flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $307 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$312 Roundtrip, found 3 hours ago

$312

Roundtrip

found 3 hours ago

Select Delta flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $312 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$314 Roundtrip, found 3 hours ago

$314

Roundtrip

found 3 hours ago

Select United flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $314 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$316 Roundtrip, found 3 hours ago

$316

Roundtrip

found 3 hours ago

Select American Airlines flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $316 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$318 Roundtrip, found 3 hours ago

$318

Roundtrip

found 3 hours ago

Select United flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $318 found 3 hours ago

Sun, Oct 12 - Sat, Oct 18

ORD

O'Hare Intl.

CHS

Charleston Intl.

$367 Roundtrip, found 3 hours ago

$367

Roundtrip

found 3 hours ago

Select Spirit Airlines flight, departing Sun, Oct 12 from O'Hare Intl. to Charleston Intl., returning Sat, Oct 18, priced at $367 found 3 hours ago