$305 Cheap American Airlines flights San Francisco (SFO) to St. Louis (STL)

View $305 flight on Mon, Dec 29, 2025Opens in a new window

$305 Cheap American Airlines flights San Francisco (SFO) to St. Louis (STL)

Prices were available within the past 7 days and start at $305 for one-way flights and $531 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Mon, Dec 29 - Wed, Dec 31
SFO
San Francisco
STL
St. Louis
$531 Roundtrip, found 16 hours ago
$531
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Mon, Dec 29 from San Francisco to St. Louis, returning Wed, Dec 31, priced at $531 found 16 hours ago
American Airlines
Mon, Dec 29 - Wed, Dec 31
SFO
San Francisco
STL
St. Louis
$576 Roundtrip, found 16 hours ago
$576
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Mon, Dec 29 from San Francisco to St. Louis, returning Wed, Dec 31, priced at $576 found 16 hours ago
American Airlines
Mon, Dec 29 - Wed, Dec 31
SFO
San Francisco
STL
St. Louis
$581 Roundtrip, found 16 hours ago
$581
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Mon, Dec 29 from San Francisco to St. Louis, returning Wed, Dec 31, priced at $581 found 16 hours ago
American Airlines
Mon, Dec 29 - Wed, Dec 31
SFO
San Francisco
STL
St. Louis
$605 Roundtrip, found 16 hours ago
$605
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Mon, Dec 29 from San Francisco to St. Louis, returning Wed, Dec 31, priced at $605 found 16 hours ago
American Airlines
Fri, Dec 26 - Tue, Jan 6
SFO
San Francisco
STL
St. Louis
$680 Roundtrip, found 16 hours ago
$680
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Fri, Dec 26 from San Francisco to St. Louis, returning Tue, Jan 6, priced at $680 found 16 hours ago

Find the cheapest month to fly from San Francisco (SFO) to St. Louis (STL)

February is typically the cheapest month to fly

From $120 - $404 per traveler.

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $352
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $352
Flights from San Francisco (SFO) to St. Louis (STL)
Origin airport
San Francisco Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Frontier Airlines, Hawaiian Airlines, Southwest Airlines, United
Popular airline
Delta
Distance
2771 km
Average flight time
5 hours 54 mins