Isla Grande Vacations
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Isla Grande Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Hotel Casa Panamá
Casco Viejo
$946
per person
Oct 22 - Oct 27
found 9 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Stay at this hotel in Panama City. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Overall a good place to stay for exploring Panama. Lots of restaurants and activities walking distance.
Reviewed on Sep 16, 2026
Megapolis Hotel Panamá
San Francisco
$1,159
per person
Oct 22 - Oct 27
found 9 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Riande Aeropuerto Hotel & Casino
Tocumen Airport
$1,028
per person
Oct 22 - Oct 27
found 9 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
Limpio, facilísimo de llegar y de regresar, los uber barato desde el aeropuerto al hotel y el bus excelente
Reviewed on Sep 18, 2026
Hyatt Regency Panama City
Bella Vista
$1,095
per person
Oct 22 - Oct 27
found 9 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Las Clementinas
Casco Viejo
$1,174
per person
Oct 22 - Oct 27
found 9 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Stay at this aparthotel in Panama City. Enjoy free WiFi, parking (surcharge), and an airport shuttle (surcharge). Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
It was a charming property and the check in staff was helpful and polite. Room was clean but there was a musty smell in the bedroom and the air conditioning was very loud. I suppose because it is an older property.
Reviewed on Sep 6, 2026
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
$1,356
per person
Oct 22 - Oct 27
found 9 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions Panama Viejo and Multiplaza Pacific Mall are located nearby.
Upscale modern rooms, nice pool and gym, free valet parking, great breakfast buffet, and nice shopping center next door.
Reviewed on Sep 16, 2026
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View all tripsIsla Grande Vacation Packages
Trying to figure out a way to bundle your flight and hotel, while saving some money? The AARP Travel Center Powered by Expedia® Isla Grande vacation packages can help. We're here to book everything you'll need to make your Isla Grande trip one to remember. Our Travel Center is a one-stop shop where you can put together the best Isla Grande vacation package for you and your family. AARP Travel Center has an amazing choice of accommodations and flight, and Isla Grande activities to choose from.
Isla Grande Hotels
With 61 hotels and resorts in Isla Grande to choose from, you will find one that is perfect for you.
From Isla Grande hotels with multiple pools and on-site restaurants, to boutique accommodations that add all the extra amenities, you'll find a hotel here that will make your trip astounding. With AARP Travel Center's Isla Grande hotel packages, you not only get a great rate on your flight, but also a wonderful place to stay.
Things to do in Isla Grande
People from all over make this city their vacation destination, and with good reason. A little curiosity and asking the right people, like your hotel's concierge, goes a long way into having a unique experience.
If you need more suggestions, then make sure to click on AARP's "Things to Do" tab.
Save with a Isla Grande Vacation Package
As an AARP Member, you can benefit from all the great savings. You'll save on select hotels worldwide, flights, and rental cars. No matter what Isla Grande vacation bundle you choose, you can rest easy knowing that you already saved on your trip. So what are you waiting for? Book today and get ready for your Isla Grande vacation.
Top Hotel Deals
Ordovician Beach Resort
Isla Grande Isla Grande Colon
Book a stay at this luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park ...
HOTEL ISLA GRANDE
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
Stay at this hotel in Isla Grande. Enjoy free breakfast, onsite spa services, and daily housekeeping. Popular attractions Isla Mamey and Portobelo National Park ...
Hotel Cocotal
La Guaira Isla Grande Provincia de Colón
Stay at this hotel in Isla Grande. Enjoy free breakfast, free WiFi, and 20 restaurants. Popular attractions Isla Mamey and Portobelo National Park are located ...
Brother Sun Villas
Camino Al Faro Isla Grande
Book a stay at this beach vacation home in Isla Grande. Enjoy a beach locale, daily housekeeping, and a garden. Popular attractions Isla Mamey and Portobelo ...
Casa Congo - Rayo Verde - Restaurante
Calle Genea Portobelo
Book a stay at this beach B&B in Portobelo. Enjoy free breakfast, an airport shuttle (surcharge), and daily housekeeping. Popular attractions Fuerte San Jerónimo ...
Ranchos de Chalia
Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón
Stay at this hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located ...
Ciel y Miel
Caillle Principale Cacique Provincia de Colón
Book a stay at this beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park ...
ScubaPortobelo
Vía Portobelo, Colón Portobelo Provincia de Colón
Stay at this hostel in Portobelo. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Fuerte Santiago and Real Aduana de Portobelo ...
La Posada del Buzo
Vía Portobelo Portobelo Provincia de Colón
Stay at this hotel in Portobelo. Enjoy free WiFi, breakfast (surcharge), and a beach shuttle (surcharge). Popular attractions Fuerte Santiago and Fuerte San ...
Villa Bella Portobelo
Buenaventura Portobelo Colón
Book a stay at this beach hostel in Portobelo. Enjoy free WiFi, a private beach, and breakfast (surcharge). Popular attractions Fuerte Santiago and Fuerte San ...
Vicina Maris Beach Lodge
Playa La Angosta Maria Chiquita Colón
Stay at this B&B in Maria Chiquita. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Playa La Angosta and Safarick's Zoo are located ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Mon, Jan 25 - Tue, Jan 26
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$264
Roundtrip
found 1 day ago
Mon, Jan 25 - Tue, Jan 26
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$290
Roundtrip
found 1 day ago
Fri, Jan 29 - Tue, Feb 9
MIA
Miami Intl.
PTY
Tocumen Intl.
$502
Roundtrip
found 3 days ago
Tue, Dec 1 - Sat, Dec 5
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$517
Roundtrip
found 1 day ago
Sat, Jan 30 - Sat, Feb 6
MIA
Miami Intl.
PTY
Tocumen Intl.
$561
Roundtrip
found 3 days ago
Best points of interest in Isla Grande
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