
Cayos Los Grullos Vacation Packages for 2026
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Cayos Los Grullos Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

Hotel Casa Panamá
Casco Viejo
Price was $1,282, price is now $926 per person
$926
per person
Jan 24 - Jan 31
found 3 hours ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Stay at this hotel in Panama City. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Casa Panama Hotel has an excellent location in Casco Viejo, and the staff kindly held our luggage. However, the rooms are small, and the hotel shares an elevator with the restaurant upstairs. Overall, it was an okay stay for one night, with the location being the main highlight. The pool is on the roof in the middle of the restaurant. Wi-fi was very spotty.
Reviewed on Oct 29, 2026

Megapolis Hotel Panamá
San Francisco
Price was $3,042, price is now $1,333 per person
$1,333
per person
Jan 24 - Jan 31
found 3 hours ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Thanks
Reviewed on Nov 3, 2026

Riande Aeropuerto Hotel & Casino
Tocumen Airport
Price was $1,622, price is now $1,039 per person
$1,039
per person
Jan 24 - Jan 31
found 3 hours ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
Le personnel très gentil - mais pas d'eau chaude
Reviewed on Nov 2, 2026

Hyatt Regency Panama City
Bella Vista
Price was $2,358, price is now $1,575 per person
$1,575
per person
Jan 24 - Jan 31
found 3 hours ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.

Hotel Riu Plaza Panama
Bella Vista
Price was $1,580, price is now $1,067 per person
$1,067
per person
Jan 24 - Jan 31
found 3 hours ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Had a great week’s stay at the hotel and it was great, very clean and helpful staff. Will definitely recommend and return.
Reviewed on Nov 3, 2026

Sheraton Grand Panama
San Francisco
Price was $1,424, price is now $1,100 per person
$1,100
per person
Jan 24 - Jan 31
found 3 hours ago
Roundtrip non-stop flight included
Washington (WAS) to Panama City (PTY)
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Multiplaza Pacific Mall are located nearby.
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See all available trips from Columbus to Cayos Los Grullos
View all tripsTop Hotel Deals

San Blas Private Beach Cabin
Nusatupo Narganá Guna Yala
0.56 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna ...

San Blas Private Over-the-Water Cabin
Nusatupo Narganá Guna Yala
0.56 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna ...

glampling sanblas luxury
Mar Caribe Nargana
0.08 km from city center
Stay at this campground in Narganá. Enjoy free breakfast, free WiFi, and room service. Popular attraction Museum of the Kuna Nation is located nearby.

Pelicano Island
Moraquedub Moraquedub Guna Yala
0.32 km from city center
Stay at this cabin in Narganá. Enjoy free WiFi, a picnic area, and balconies. Popular attraction Museum of the Kuna Nation is located nearby.

Cabanas Narasgandub - Naranjo Chico
Kuna Yala Narganá Guna Yala
0.59 km from city center
Book a stay at this beach hotel in Narganá. Enjoy free breakfast, a 24-hour front desk, and an airport shuttle (surcharge). Popular attraction Museum of the ...

Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island Narganá Guna Yala
10.39 km from city center
Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attractions Isla Diablo and Isla Chichime ...

san blas luxury tour
guna yala Nusatupo Guna Yala
9.03 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, free WiFi, and a private beach.

Cocoloco - Catamaran Lagoon 52F SAN BLAS
El Porvenir Narganá Guna Yala
16.92 km from city center
Stay at this cruise ship in San Blas Islands. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions Porvenir Museum and Isla Chichime ...

Konsenda San Blas
Llano Cartí Km 11 El Llano Panamá Province
30.65 km from city center
Stay at this hotel in El Llano. Enjoy free breakfast, free parking, and a garden.

San Blas Tour Aridub
Urgandi, Guna Yala, Panamá Narganá Guna Yala
8.9 km from city center
Book a stay at this beach cabin in Narganá. Enjoy beach cabanas (surcharge), a beach shuttle (surcharge), and daily housekeeping.

Private Bedroom on Paradise San Blas Island
Isla Yansailadup Narganá Guna Yala
9.87 km from city center
Stay at this guesthouse in Narganá. Enjoy free breakfast, an airport shuttle (surcharge), and a picnic area. Popular attractions Isla Diablo and Museum of the ...

Private Over-Water Cabins on San Blas Island
C5W9 4M Nusatupo Narganá
7.49 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna ...

San Blas Private Oceanfront Cabin
C5W9 4M Nusatupo Narganá Guna Yala
9.03 km from city center
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge).
Don't see what you're looking for?
See all available properties in Cayos Los Grullos
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Jan 25 - Tue, Jan 26
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$264 Roundtrip, found 1 day ago
$264
Roundtrip
found 1 day ago

Mon, Jan 25 - Tue, Jan 26
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$315 Roundtrip, found 1 day ago
$315
Roundtrip
found 1 day ago

Fri, Jan 1 - Thu, Jan 21
MIA
Miami Intl.
PTY
Tocumen Intl.
$597 Roundtrip, found 5 days ago
$597
Roundtrip
found 5 days ago

Mon, Dec 28 - Tue, Jan 12
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$704 Roundtrip, found 19 hours ago
$704
Roundtrip
found 19 hours ago

Tue, Jul 20 - Fri, Jul 30
JFK
John F. Kennedy Intl.
PTY
Tocumen Intl.
$775 Roundtrip, found 3 days ago
$775
Roundtrip
found 3 days ago

