Vacations Close To Sistine Chapel

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Sistine Chapel Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Tree Charme Augusto Boutique Hotel

Tree Charme Augusto Boutique Hotel

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $2,444, price is now $1,638 per person
$1,638
per person
Oct 27 - Nov 1
found 4 hours ago
Roundtrip non-stop flight included
St. Louis (STL) to Rome (FCO)

Borghese Contemporary Hotel

Borghese Contemporary Hotel

4 out of 5
Rome City Centre
Save 100% on your flight
Price was $3,189, price is now $2,145 per person
$2,145
per person
Oct 27 - Nov 1
found 4 hours ago
Roundtrip non-stop flight included
St. Louis (STL) to Rome (FCO)
Hi. Can’t say enough nice things about this hotel. It’s a perfectly positioned property so you are within walking distance of most attractions. It a boutique hotel so it’s small but everything is spaced out nicely and it has everything you could need for an extended stay. Khaled the main concierge gentleman was exceptional. He helped us with everything we needed and even went above and beyond to call our tour company when our flight was 10 hours delayed. FYI avoid United airlines at all costs. It’s the third time going to Europe that we have experienced major delays!! We would highly recommend this hotel to anyone traveling to Rome. We will be back for our next trip to Rome. Thanks again!!

Reviewed on Sep 12, 2026

TB Place Roma

TB Place Roma

4 out of 5
Rome City Centre
Save 100% on your flight
Price was $3,312, price is now $2,320 per person
$2,320
per person
Oct 27 - Nov 1
found 4 hours ago
Roundtrip non-stop flight included
St. Louis (STL) to Rome (FCO)
The room was cleaned well each day, beds made

Reviewed on Sep 14, 2026

Palazzo Ripetta

Palazzo Ripetta

5 out of 5
Rome City Centre
Save 100% on your flight
Price was $3,906, price is now $2,880 per person
$2,880
per person
Oct 27 - Nov 1
found 4 hours ago
Roundtrip non-stop flight included
St. Louis (STL) to Rome (FCO)

Je Rome Hotel

Je Rome Hotel

4 out of 5
Rome City Centre
Price was $2,384, price is now $1,797 per person
$1,797
per person
Oct 27 - Nov 1
found 4 hours ago
Roundtrip non-stop flight included
St. Louis (STL) to Rome (FCO)

Hotel Adriano Rooftop

Hotel Adriano Rooftop

4 out of 5
Rome City Centre
Price was $2,323, price is now $1,755 per person
$1,755
per person
Oct 27 - Nov 1
found 4 hours ago
Roundtrip non-stop flight included
St. Louis (STL) to Rome (FCO)

Elizabeth Unique Rome - a Member of Design Hotels

Elizabeth Unique Rome - a Member of Design Hotels

5 out of 5
Rome City Centre
Save 100% on your flight
Price was $3,478, price is now $2,695 per person
$2,695
per person
Oct 27 - Nov 1
found 4 hours ago
Roundtrip non-stop flight included
St. Louis (STL) to Rome (FCO)

The First Dolce - Preferred Hotels & Resorts

The First Dolce - Preferred Hotels & Resorts

5 out of 5
Rome City Centre
Save 100% on your flight
Price was $5,720, price is now $4,437 per person
$4,437
per person
Oct 27 - Nov 1
found 4 hours ago
Roundtrip non-stop flight included
St. Louis (STL) to Rome (FCO)
Excellent service and staff!

Reviewed on Sep 16, 2026

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Best Lodging Options Near Sistine Chapel

Vatican Style

Vatican Style

Via del Mascherino 46 Rome RM
0.38 km from Sistine Chapel
Book a stay at this luxury guesthouse in Rome. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
Hotel Pacific Roma

Hotel Pacific Roma

3 out of 5
Viale delle Medaglie D'Oro 51 Rome RM
1.09 km from Sistine Chapel
Stay at this hotel in Rome. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Mama Shelter Roma

Mama Shelter Roma

4 out of 5
Via Luigi Rizzo 20 Rome RM
0.96 km from Sistine Chapel
Book a stay at this spa hotel in Rome. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the breakfast and the restaurant in our reviews. ...
Hotel Delle Nazioni

Hotel Delle Nazioni

4 out of 5
Via Poli 7 Rome RM
2.34 km from Sistine Chapel
Book a stay at this business-friendly hotel in Rome. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
Grand Hotel Olympic

Grand Hotel Olympic

4 out of 5
Via Properzio 2/a Rome RM
0.7 km from Sistine Chapel
Stay at this hotel in Rome. Enjoy free breakfast, free WiFi, and 24-hour room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Starhotels Michelangelo

Starhotels Michelangelo

4 out of 5
Via Della Stazione Di San Pietro 14 Rome RM
0.45 km from Sistine Chapel
Book a stay at this family-friendly hotel in Rome. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
Trastevere Roma | UNA Esperienze | Preferred Hotels and Resorts

Trastevere Roma | UNA Esperienze | Preferred Hotels and Resorts

4 out of 5
Via Emilio Morosini 27 Rome RM
2.24 km from Sistine Chapel
Stay at this hotel in Rome. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the breakfast and the bar in our reviews. Popular ...
Hotel Abruzzi

Hotel Abruzzi

3 out of 5
Piazza Della Rotonda 69 Rome RM
1.92 km from Sistine Chapel
Stay at this hotel in Rome. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.