Business Hotels in Wytheville 2026
Photo by Meng Fan
Featured Wytheville Business Hotels
Comfort Suites Wytheville
695 Peppers Ferry Rd Wytheville VA
Days Inn by Wyndham Wytheville
150 Malin Dr, I-81 and I-77 Exit 73 Wytheville VA
Deluxe Inn Wytheville
355 Nye Road Wytheville VA
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Ramada by Wyndham Wytheville
955 Peppers Ferry Rd Wytheville VA
Sleep Inn Wytheville I-77 and I-81
135 Nye Cir Wytheville VA
Spark by Hilton Wytheville Holston Rd I 81
315 Holston Rd Wytheville VA
Fully refundableReserve now, pay when you stay
Country Inn & Suites by Radisson, Wytheville, VA
697 Peppers Ferry Road Wytheville VA
Fairfield Inn & Suites by Marriott
200 Marriott Way Wytheville VA
Fully refundableReserve now, pay when you stay
Hampton Inn Ft. Chiswell-Max Meadows
199 Fort Chiswell Rd Max Meadows VA
Fully refundableReserve now, pay when you stay
Hampton Inn Wytheville
950 Pepper's Ferry Rd Wytheville VA
Fully refundableReserve now, pay when you stay
Holiday Inn Express and Suites Wytheville by IHG
165 Malin Dr Wytheville VA
Fully refundable
Garner Hotel Wytheville East by IHG
1800 East Main Street Wytheville VA
Spark by Hilton Wytheville East Main Street
2015 East Main Street Wytheville VA
Fully refundableReserve now, pay when you stay
The Bolling Wilson Hotel
170 East Main Street Wytheville VA
Fully refundableReserve now, pay when you stay
Travelodge by Wyndham Wytheville
140 Lithia Rd Wytheville VA
Quality Inn & Suites
1900 E Main St Wytheville VA
Edyn Hotel By Townhouse Wytheville US 52
280 Lithia Rd Wytheville VA
Fully refundableReserve now, pay when you stay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.