Cheap 2026 Serra Mesa Hotels
Choose from 9077 Serra Mesa Hotel Deals
Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
10.05 km from Serra Mesa
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Lafayette Hotel & Club
2223 El Cajon Blvd San Diego CA
Free Cancellation
Reserve now, pay when you stay
5.34 km from Serra Mesa
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. ...
The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue San Diego CA
Free Cancellation
Reserve now, pay when you stay
9.25 km from Serra Mesa
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Legacy Resort Hotel & Spa
875 Hotel Circle South San Diego CA
Free Cancellation
Reserve now, pay when you stay
5.68 km from Serra Mesa
Book a stay at this spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
Hard Rock Hotel San Diego
207 5th Ave San Diego CA
Free Cancellation
Reserve now, pay when you stay
10.75 km from Serra Mesa
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
Best Western Plus Marina Gateway Hotel
800 Bay Marina Dr National City CA
Free Cancellation
Reserve now, pay when you stay
16.15 km from Serra Mesa
Book a stay at this golf hotel in National City. Enjoy free WiFi, free parking, and a golf course. Our guests praise the pool and the restaurant in our reviews. ...
San Diego Marriott La Jolla
4240 La Jolla Village Dr La Jolla CA
Free Cancellation
Reserve now, pay when you stay
10.64 km from Serra Mesa
Book a stay at this business-friendly hotel in La Jolla. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests praise ...
Courtyard by Marriott San Diego Downtown Little Italy
1646 Front St San Diego CA
Free Cancellation
9.29 km from Serra Mesa
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
12.59 km from Serra Mesa
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
9.85 km from Serra Mesa
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Hilton San Diego Mission Valley
901 Camino Del Rio S San Diego CA
Free Cancellation
Reserve now, pay when you stay
4.67 km from Serra Mesa
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Embassy Suites by Hilton San Diego La Jolla
4550 La Jolla Village Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
10.34 km from Serra Mesa
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, 2 restaurants, and a free beach shuttle. Our guests praise the breakfast and ...
Hampton Inn & Suites by Hilton San Diego SeaWorld
3888 Greenwood St San Diego CA
Free Cancellation
Reserve now, pay when you stay
8.16 km from Serra Mesa
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Popular attractions Mission Bay and Port of ...
The Dana on Mission Bay
1710 W Mission Bay Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
10.12 km from Serra Mesa
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
Pendry San Diego
550 J Street San Diego CA
Free Cancellation
Reserve now, pay when you stay
10.57 km from Serra Mesa
Book a stay at this luxury hotel in San Diego. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Serra Mesa, San Diego Hotel Guide
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