Photo by Kaylee Spinhirn

Featured Vacation Homes in Salem

The Winona House - Boutique Hotel Near Downtown

Stay at this vacation home in Roanoke. Popular attractions The River Rock and Shaftman Performance Hall are located nearby.

Fully Furnished 4-bedroom Located on a Quiet Block

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Stay at this 3.5-star vacation home in Roanoke. Enjoy free WiFi, free parking, and a garden. Popular attractions Virginia Museum of Transportation and Berglund ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Baymont by Wyndham Salem Roanoke Area

179 Sheraton Drive, I-81 Exit 141, Salem, VA

La Quinta Inn & Suites by Wyndham Roanoke Salem

140 Sheraton Dr, Salem, VA

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.