Business Hotels in Portsmouth 2025
Photo by Tyler Estle
Featured Portsmouth Business Hotels
Quality Inn
8226 Ohio River Rd, Wheelersburg, OH
Quality Inn & Suites
5100 Old Scioto Trail, Portsmouth, OH
Holiday Inn Portsmouth Downtown by IHG
711 2nd St, Portsmouth, OH
Fully refundable
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Super 8 by Wyndham Portsmouth
4266 US Route 23 N, Portsmouth, OH
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.