Santa Ana

Panama City

A gazebo with columns, a large tree with hanging roots, and a building in the background.

A waterfront cityscape with numerous boats docked along the shore and a clear sky.

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Things to do

Hotels

Panama City Travel Guide

Stay near popular Santa Ana attractions

El Machetazo Santa Ana

You can search for that perfect souvenir at El Machetazo Santa Ana during your trip to Panama City. Amble around the area's parks or visit its shops.

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Things to do

Panama Canal: The Most Complete Monkey Island Experience

Panama Canal: The Most Complete Wildlife Experience

$60

per adult

96% of travellers recommend

Panama City: Zip Line Experience Over The City

$40

per adult

96% of travellers recommend

Panama City Visit an Indian town Embera and waterfall with lunch

$52

per adult

98% of travellers recommend

Panama Canal Partial Transit

$150

per adult

86% of travellers recommend

Half day of Panama city and canal tour: shared and private

$67

per adult

96% of travellers recommend

From Panama City: Monkey Islands Tour on Gatun Lake

$30

per adult

94% of travellers recommend

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Santa Ana Hotel Deals

Casco View Apartments

C. 16 Oeste Panama City Provincia de Panamá

Book a stay at this business-friendly condo in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping ...

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Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...

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Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama

Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...

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Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...

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Dreams Playa Bonita Panama - All Inclusive

KM 7, Road to Veracruz Veracruz Panama

Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...

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Megapolis Hotel Panamá

Avenida Balboa Panama City

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...

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See all 1,802 properties in Santa Ana

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. Learn more about Santa Ana

A coastal cityscape with buildings, a hill with a church, and a clear blue sky.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

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A spiraling skyscraper against a clear blue sky.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.

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A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

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