Business Hotels in Muscatine 2026
Photo by Bill Eaker
Featured Muscatine Business Hotels
Hampton Inn Muscatine
3303 N Port Drive Muscatine IA
Fully refundableReserve now, pay when you stay
AmericInn by Wyndham Muscatine
3115 Hwy 61 North Muscatine IA
Comfort Inn Muscatine near Hwy 61
115 Cleveland St Muscatine IA
Save an average of 15% on thousands of hotels when you're signed in
Best Western Muscatine / Pearl City Hotel
305 Cleveland St Muscatine IA
Fully refundableReserve now, pay when you stay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.