Vacations Close To Main Street

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Main Street Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
Medical Center District
Price was $739, price is now $556 per person
$556
per person
Sep 19 - Sep 26
found 2 hours ago
Roundtrip non-stop flight included
San Francisco (SFO) to San Antonio (SAT)

Hotel Contessa

Hotel Contessa

4 out of 5
Downtown San Antonio
Save 100% on your flight
Price was $1,643, price is now $1,167 per person
$1,167
per person
Sep 20 - Sep 26
found 3 hours ago
Roundtrip flight included
San Francisco (SFO) to San Antonio (SAT)
Na

Reviewed on Aug 19, 2026

Crockett Hotel

Crockett Hotel

3 out of 5
Downtown San Antonio
Price was $1,006, price is now $790 per person
$790
per person
Sep 19 - Sep 26
found 2 hours ago
Roundtrip non-stop flight included
San Francisco (SFO) to San Antonio (SAT)

The O'Brien Riverwalk Hotel, Trademark Collection by Wyndham

The O'Brien Riverwalk Hotel, Trademark Collection by Wyndham

3.5 out of 5
Downtown San Antonio
Price was $892, price is now $713 per person
$713
per person
Sep 19 - Sep 26
found 2 hours ago
Roundtrip non-stop flight included
San Francisco (SFO) to San Antonio (SAT)

Landing Apartments San Antonio near Baptist Neighborhood Hospital

Landing Apartments San Antonio near Baptist Neighborhood Hospital

3 out of 5
South San Antonio
Price was $1,050, price is now $866 per person
$866
per person
Sep 27 - Oct 4
just found
Roundtrip non-stop flight included
San Francisco (SFO) to San Antonio (SAT)

Hotel Gibbs Downtown Riverwalk

Hotel Gibbs Downtown Riverwalk

2 out of 5
Downtown San Antonio
Price was $950, price is now $786 per person
$786
per person
Sep 19 - Sep 26
found 2 hours ago
Roundtrip non-stop flight included
San Francisco (SFO) to San Antonio (SAT)
Stayed in the Junior Suite and it was much bigger than expected. The bathroom was huge! Very clean. Perfect location to river without being on a busy street. Will stay again.

Reviewed on Aug 19, 2026

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
Medical Center District
Price was $857, price is now $717 per person
$717
per person
Sep 20 - Sep 27
found 2 hours ago
Roundtrip flight included
San Francisco (SFO) to San Antonio (SAT)

Staybridge Suites San Antonio by IHG

Staybridge Suites San Antonio by IHG

3 out of 5
Uptown
Price was $918, price is now $769 per person
$769
per person
Sep 27 - Oct 4
just found
Roundtrip non-stop flight included
San Francisco (SFO) to San Antonio (SAT)
There were roaches in both rooms we rented. Gross, woke up at 2am to roaches in the bed!!!!!

Reviewed on Aug 16, 2026

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Best Lodging Options Near Main Street

Fredericksburg Inn & Suites

Fredericksburg Inn & Suites

2.5 out of 5
201 S Washington Fredericksburg TX
0.77 km from Main Street
Book a stay at this business-friendly hotel in Fredericksburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
Albert Hotel

Albert Hotel

4 out of 5
213 East Austin Street Fredericksburg TX
0.47 km from Main Street
Book a stay at this spa hotel in Fredericksburg. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Popular attractions National Museum of the Pacific ...
Sunday House Inn and Suites

Sunday House Inn and Suites

2 out of 5
501 E Main Street Fredericksburg TX
0.97 km from Main Street
Stay at this hotel in Fredericksburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular ...
Inn On Barons Creek

Inn On Barons Creek

2.5 out of 5
308 South Washington Street Fredericksburg TX
0.81 km from Main Street
Book a stay at this business-friendly hotel in Fredericksburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Peach Tree Inn & Suites

Peach Tree Inn & Suites

2.5 out of 5
401 S Washington St Fredericksburg TX
0.87 km from Main Street
Stay at this motel in Fredericksburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient parking in our ...
Wine Country Inn

Wine Country Inn

2 out of 5
705 S Washington Street Fredericksburg TX
1.6 km from Main Street
Stay at this hotel in Fredericksburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
Onera Fredericksburg

Onera Fredericksburg

4 out of 5
173 Basse Ln Fredericksburg TX
1.93 km from Main Street
Stay at this hotel in Fredericksburg. Enjoy free WiFi, free parking, and a sauna. Popular attractions Pioneer Museum and Fredericksburg Winery are located ...
Charming Cottage Near Main With Patio&firepit!!

Charming Cottage Near Main With Patio&firepit!!

3 out of 5
Fredericksburg TX
0.78 km from Main Street
Stay at this vacation home in Fredericksburg. Enjoy balconies or patios, an in-room coffeemaker, and air conditioning. Popular attractions Pioneer Museum and ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.