
Lake City Vacations
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals

The Inn at the Crossroads
128 West Main Street Lake City SC
0.16 km from city center
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Quality Inn & Suites Lake City
202 N Ron Mcnair Blvd Lake City SC
0.81 km from city center
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

Days Inn by Wyndham Lake City
170 S Ron Mcnair Blvd Lake City SC
0.64 km from city center
Book a stay at this business-friendly motel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Lynches Lake Historical Society ...

Security inn & suites
319 Sumter St Lake City SC
0.88 km from city center
Stay at this hotel in Lake City. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Lynches Lake Historical Society and The Bean Market ...

Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
35.46 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...

TownePlace Suites by Marriott Florence
2650 Hospitality Boulevard Florence SC
35.63 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful ...

Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr Florence SC
36.35 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

SpringHill Suites by Marriott Florence
2670 Hospitality Blvd Florence SC
35.65 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
3440 W Radio Dr Florence SC
35.81 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Fairfield Inn & Suites by Marriott Florence I-20
501 Woody Jones Boulevard Florence SC
35.43 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...

Residence Inn Marriott Florence
2660 Hospitality Blvd Florence SC
35.72 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...

Home2 Suites by Hilton Florence, SC
900 Woody Jones Blvd Florence SC
35.51 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Hilton Garden Inn Florence
2671 Hospitality Boulevard Florence SC
35.75 km from city center
Book a stay at this family-friendly hotel in Florence. Enjoy room service, a fitness center, and a garden. Our guests praise the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Apr 15 - Tue, Apr 21
TPA
Tampa Intl.
FLO
Florence Regional
$597 Roundtrip, found 4 days ago
$597
Roundtrip
found 4 days ago

Mon, Apr 13 - Tue, Apr 21
TPA
Tampa Intl.
FLO
Florence Regional
$632 Roundtrip, found 4 days ago
$632
Roundtrip
found 4 days ago

Mon, Apr 13 - Sun, Apr 19
TPA
Tampa Intl.
FLO
Florence Regional
$667 Roundtrip, found 4 days ago
$667
Roundtrip
found 4 days ago

Tue, Apr 14 - Wed, Apr 15
TPA
Tampa Intl.
FLO
Florence Regional
$803 Roundtrip, found 4 days ago
$803
Roundtrip
found 4 days ago

