Lake City Vacations
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals
The Inn at the Crossroads
128 West Main Street, Lake City, SC
0.16 km from city center
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Quality Inn & Suites
202 N Ron Mcnair Blvd, Lake City, SC
0.79 km from city center
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Days Inn by Wyndham Lake City
170 S Ron Mcnair Blvd, Lake City, SC
0.64 km from city center
Book a stay at this business-friendly motel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Lynches Lake Historical Society ...
Security inn & suites
319 Sumter St, Lake City, SC
0.88 km from city center
Stay at this hotel in Lake City. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Lynches Lake Historical Society and The Bean Market ...
Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr, Florence, SC
36.35 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Comfort Inn & Suites
527 Woody Jones Blvd, Florence, SC
35.45 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr, Florence, SC
36.3 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Hampton Inn & Suites Florence Center
3000 W Radio Dr, Florence, SC
36.2 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
3440 W Radio Dr, Florence, SC
35.81 km from city center
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Aloft Florence
820 WOODY JONES BOULEVARD, Florence, SC
35.44 km from city center
Stay at this 3-star business-friendly hotel in Florence. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Florence Veterans Park ...
Red Roof Inn Florence - Civic Center
2690 David H McLeod Boulevard, Florence, SC
35.94 km from city center
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
Home2 Suites by Hilton Florence, SC
900 Woody Jones Blvd, Florence, SC
35.56 km from city center
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Courtyard by Marriott Florence
2680 Hospitality Blvd, Florence, SC
35.95 km from city center
Stay at this 3-star business-friendly hotel in Florence. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Wed, Jun 18 - Sat, Jun 28
TPA
Tampa Intl.
FLO
Florence Regional
$387 Roundtrip, found 23 hours ago
$387
Roundtrip
found 23 hours ago
Wed, Jun 18 - Sat, Jun 28
TPA
Tampa Intl.
FLO
Florence Regional
$447 Roundtrip, found 23 hours ago
$447
Roundtrip
found 23 hours ago
Wed, Jun 18 - Sat, Jun 28
TPA
Tampa Intl.
FLO
Florence Regional
$452 Roundtrip, found 23 hours ago
$452
Roundtrip
found 23 hours ago
Wed, Jun 18 - Sat, Jun 28
TPA
Tampa Intl.
FLO
Florence Regional
$492 Roundtrip, found 23 hours ago
$492
Roundtrip
found 23 hours ago
Best points of interest in Lake City
- Lions Park Vacations
- Moore Farms Botanical Garden Vacations
- Ronald E. McNair Life History Center Vacations
- The Country Club at Lake City Vacations
- The Bean Market Vacations
- Lynches Lake Historical Society Vacations
- Florence Civic Center Vacations
- Magnolia Mall Vacations
- Francis Marion University Vacations
- Florence Museum Vacations
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All accommodation types in Lake City
More Types of Hotels
- Hotels with WiFi in Lake City
- Lakefront Hotels in Lake City
- Smoke Free Hotels in Lake City
- Hotel with wifi in Lake City
- Hotels with Air Conditioning in Lake City
- Family Hotels in Lake City
- Hotels with Balconies in Lake City
- Hotels with Bars in Lake City
- Hotels with a Pool in Lake City
- Hotels with Complimentary Breakfast in Lake City
- Cheap Hotels in Lake City
- Pet-friendly Hotels in Lake City
- Beach Hotels in Lake City