Lake City Vacations
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals
The Inn at the Crossroads
128 West Main Street Lake City SC
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Quality Inn & Suites Lake City
202 N Ron Mcnair Blvd Lake City SC
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Days Inn by Wyndham Lake City
170 S Ron Mcnair Blvd Lake City SC
Book a stay at this business-friendly motel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Lynches Lake Historical Society ...
Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
SpringHill Suites by Marriott Florence
2670 Hospitality Blvd Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean ...
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Hampton Inn & Suites Florence Center
3000 W Radio Dr Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
3440 W Radio Dr Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Staybridge Suites Florence - Civic Center by IHG
150 Westpark Drive Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
TownePlace Suites by Marriott Florence
2650 Hospitality Boulevard Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful ...
Aloft by Marriott Florence
820 WOODY JONES BOULEVARD Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Popular attractions Regal Swamp ...
Fairfield Inn & Suites by Marriott Florence I-20
501 Woody Jones Boulevard Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Courtyard by Marriott Florence
2680 Hospitality Blvd Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff and ...
Affordable Suites Florence
530 Woody Jones Blvd Florence SC
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and 4 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions Florence ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Wed, Oct 28 - Wed, Nov 4
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$363
Roundtrip
found 1 day ago
Sun, Oct 25 - Wed, Nov 4
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$420
Roundtrip
found 10 hours ago
Wed, Oct 28 - Wed, Nov 4
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$443
Roundtrip
found 1 day ago
Wed, Oct 28 - Wed, Nov 4
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$495
Roundtrip
found 1 day ago
Best points of interest in Lake City
- Moore Farms Botanical Garden Vacations
- Lions Park Vacations
- The Bean Market Vacations
- Ronald E. McNair Life History Center Vacations
- Lynches Lake Historical Society Vacations
- The Country Club at Lake City Vacations
- Florence Civic Center Vacations
- Magnolia Mall Vacations
- Francis Marion University Vacations
- Florence Motor Speedway Vacations
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All accommodation types in Lake City
More Types of Hotels
- Hotels with WiFi in Lake City
- Lakefront Hotels in Lake City
- Smoke Free Hotels in Lake City
- Hotel with wifi in Lake City
- Hotels with Air Conditioning in Lake City
- Family Hotels in Lake City
- Hotels with Balconies in Lake City
- Hotels with Bars in Lake City
- Hotels with a Pool in Lake City
- Hotels with Complimentary Breakfast in Lake City
- Cheap Hotels in Lake City
- Pet-friendly Hotels in Lake City
- Beach Hotels in Lake City