Business Hotels in Lake City 2026
Featured Lake City Business Hotels
Fairfield Inn & Suites Lake City
538 Sw Corporate Dr Lake City FL
Fully refundableReserve now, pay when you stay
Holiday Inn Express & Suites Live Oak by IHG
6694 Us Highway 129 Live Oak FL
Fully refundable
Holiday Inn & Suites Lake City by IHG
213 Sw Commerce Dr Lake City FL
Fully refundable
Save an average of 15% on thousands of hotels when you're signed in
Comfort Suites Lake City
3690 W Us Highway 90 Lake City FL
Best Western Plus Lake City
350 SW Florida Gateway Dr Lake City FL
Fully refundableReserve now, pay when you stay
Quality Inn & Suites Live Oak I-10 Exit 283
6819 Us Highway 129 Live Oak FL
Hampton Inn & Suites Lake City
450 SW Florida Gateway Drive Lake City FL
Fully refundableReserve now, pay when you stay
Baymont by Wyndham Lake City I-75
3598 W Us Highway 90 Lake City FL
Home2 Suites by Hilton Lake City
414 Southwest Florida Gateway Boulevard Lake City FL
Fully refundableReserve now, pay when you stay
Quality Inn Lake City
285 Sw Commerce Dr Lake City FL
Super 8 by Wyndham Lake City
3954 SW State Road 47 Lake City FL
Americas Best Value Inn Lake City
3835 West US Highway 90 Lake City FL
Fully refundableReserve now, pay when you stay
Days Inn by Wyndham Lake City I-10
3430 N Us Highway 441 Lake City FL
Quality Inn White Springs Suwanee
3119 County Road 136 Live Oak FL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.