Photo by Geraldine Soh

Best Lodging Options Near Historic Main Street

Ameristar Casino Resort and Spa

1 Ameristar Blvd, St. Charles, MO

1.44 km from Historic Main Street

Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms and the property ...

Best Western Plus The Charles Hotel

1425 South 5th Street, St. Charles, MO

1.45 km from Historic Main Street

Stay at this 3-star business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

Country Inn & Suites by Radisson, St. Charles Historic District

1190 S Main St, St. Charles, MO

1 km from Historic Main Street

Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.