Business Hotels in Florence 2025
Featured Florence Business Hotels
Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites
1934 Highway 20, Tuscumbia, AL
Fully refundableReserve now, pay when you stay
Baymont by Wyndham Florence/Muscle Shoals
115 Ana Drive, Florence, AL
Best Western Plus Russellville Hotel & Suites
13770 Highway 43, Russellville, AL
Fully refundableReserve now, pay when you stay
Save an average of 15% on thousands of hotels when you're signed in
Comfort Suites Florence Shoals Area
140 Matthew Paul Ct, Florence, AL
Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
1852 Highway 72 E, Tuscumbia, AL
Clarion Inn Sheffield Muscle Shoals
4900 Hatch Blvd, Sheffield, AL
Hampton Inn & Suites Florence-Downtown
505 S Court St, Florence, AL
Fully refundableReserve now, pay when you stay
Hampton Inn Florence Midtown near University of North Alabama
2281 Florence Blvd, Florence, AL
Fully refundableReserve now, pay when you stay
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
180 Etta Gray Street, Florence, AL
Fully refundable
Renaissance Shoals Resort and Spa
10 Hightower Place, Florence, AL
Fully refundableReserve now, pay when you stay
Americas Best Value Inn
14184 Highway 43, Russellville, AL
Econo Lodge Russellville
13600 Highway 43, Russellville, AL
Residence Inn Florence Marriott
1000 Sweetwater Ave, Florence, AL
Fully refundableReserve now, pay when you stay
The ColdWater Inn
712 Hwy 72 W, Tuscumbia, AL
Quality Inn Florence Muscle Shoals
150 Etta Gray Drive, Florence, AL
Lake View Inn & Suites
101 Highway 72, Killen, AL
Comfort Inn & Suites Tuscumbia - Muscle Shoals
5101 Hwy 43 S, Tuscumbia, AL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.