East Prairie, MO
Travel Guide

Visit East Prairie

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...

Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Big Oak Tree State Park
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
- Big Oak Tree State Park
- Mississippi River
- Ohio River
- Ohio River Valley
- Discovery Park of America
- Reelfoot Lake State Park
- Columbus-Belmont State Park
- Sikeston Depot Museum
- River Ridge Winery
- Fort Defiance State Park
- Union City Masquerade Theatre
- Campbell's Point
- Marston Community Center
- Graham Park
- Central Park
- New Madrid Historical Museum
- Hunter-Dawson State Historic Site

