East Prairie, MO
Travel Guide
Visit East Prairie

Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Big Oak Tree State Park
4.5/5(3 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
- Big Oak Tree State Park
- Mississippi River
- Ohio River
- Reelfoot Lake State Park
- Discovery Park of America
- Columbus-Belmont State Park
- Union City Masquerade Theatre
- The Book Bug
- Graham Park
- Campbell's Point
- Sikeston Depot Museum
- Fort Defiance State Park
- New Madrid Historical Museum
- River Ridge Winery
- Marston Community Center
- Central Park
- Boot Heel Golf Club
- Front Street Studio & Art Gallery
- Hunter-Dawson State Historic Site