Cheap 2025 East Main Street Hotels
Choose from 564 East Main Street Hotel Deals
Grand Vista Hotel
2790 Crossroads Blvd, Grand Junction, CO
Free Cancellation
Reserve now, pay when you stay
5.5 km from East Main Street
Stay at this 3.5-star business-friendly hotel in Grand Junction. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the restaurant ...
Clarion Inn Grand Junction
755 Horizon Drive, Grand Junction, CO
5.29 km from East Main Street
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
La Quinta Inn & Suites by Wyndham Grand Junction
2761 Crossroads Blvd, Grand Junction, CO
5.37 km from East Main Street
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Ramada by Wyndham Grand Junction
752 Horizon Dr, I-70 at Exit 31, Grand Junction, CO
5.28 km from East Main Street
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
Doubletree Hotel Grand Junction
743 Horizon Dr, Grand Junction, CO
Free Cancellation
Reserve now, pay when you stay
4.98 km from East Main Street
Stay at this 4-star family-friendly hotel in Grand Junction. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff ...
Wine Country Inn Palisade
777 Grande River Drive, Palisade, CO
Free Cancellation
Reserve now, pay when you stay
17.11 km from East Main Street
Stay at this 3.5-star business-friendly hotel in Palisade. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
La Quinta Inn & Suites by Wyndham Fruita
570 Raptor Rd, Fruita, CO
18.8 km from East Main Street
Stay at this 3-star business-friendly hotel in Fruita. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Studio 6 Grand Junction, CO
704 Horizon Dr, Grand Junction, CO
4.44 km from East Main Street
Book a stay at this business-friendly motel in Grand Junction. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
Comfort Inn & Suites
400 Jurassic Ave, Fruita, CO
18.57 km from East Main Street
Book a stay at this golf hotel in Fruita. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
Comfort Inn Grand Junction I-70
750 3/4 Horizon Dr., Grand Junction, CO
5.35 km from East Main Street
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Courtyard by Marriott Grand Junction
765 Horizon Drive, Grand Junction, CO
Free Cancellation
Reserve now, pay when you stay
5.59 km from East Main Street
Stay at this 3-star business-friendly hotel in Grand Junction. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Hotel Maverick
840 Kennedy Avenue, Grand Junction, CO
Free Cancellation
Reserve now, pay when you stay
1.57 km from East Main Street
Stay at this 4-star hotel in Grand Junction. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the helpful staff ...
Holiday Inn and Suites Grand Junction by IHG
2751 Crossroads Blvd, Grand Junction, CO
Free Cancellation
5.41 km from East Main Street
Stay at this 3-star business-friendly hotel in Grand Junction. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Super 8 by Wyndham Fruita
399 Jurassic Ave, I-70 Exit 19, Fruita, CO
18.54 km from East Main Street
Stay at this hotel in Fruita. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Super 8 by Wyndham Grand Junction Colorado
728 Horizon Drive, Grand Junction, CO
4.83 km from East Main Street
Stay at this hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Don't see what you're looking for?
See all available properties in East Main Street
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
East Main Street, Grand Junction Hotel Guide
Search for hotels in East Main Street on Expedia.com. You can easily find your hotels in East Main Street using one of the methods below:
- View our selection of featured hotels in East Main Street
- Use the map to find hotels in the East Main Street neighborhood you prefer
- Use the filters to see hotels in a specific area of East Main Street, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in East Main Street
- Enter your travel dates to view the best deals on hotels in East Main Street - while they last
More East Main Street Hotel Deals for Seniors and Members
- Grand Vista Hotel
- Clarion Inn Grand Junction
- La Quinta Inn & Suites by Wyndham Grand Junction
- Ramada by Wyndham Grand Junction
- Doubletree Hotel Grand Junction
- Wine Country Inn Palisade
- La Quinta Inn & Suites by Wyndham Fruita
- Studio 6 Grand Junction, CO
- Comfort Inn & Suites
- Comfort Inn Grand Junction I-70