Cheap 2025 East Main Street Hotels
Choose from 573 East Main Street Hotel Deals
Grand Junction Vacation Rental w/ Fire Pit!
0.76 km from East Main Street
Stay at this 3-star business-friendly cottage in Grand Junction. Enjoy free parking and air conditioning. Popular attractions Elliott Tennis Center and Museum ...
Grand Vista Hotel
2790 Crossroads Blvd, Grand Junction, CO
Free Cancellation
Reserve now, pay when you stay
5.5 km from East Main Street
Stay at this 3.5-star business-friendly hotel in Grand Junction. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the restaurant ...
La Quinta Inn & Suites by Wyndham Grand Junction
2761 Crossroads Blvd, Grand Junction, CO
5.37 km from East Main Street
Stay at this 3-star business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Ramada by Wyndham Grand Junction
752 Horizon Dr, I-70 at Exit 31, Grand Junction, CO
5.28 km from East Main Street
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
Clarion Inn Grand Junction
755 Horizon Drive, Grand Junction, CO
5.29 km from East Main Street
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
Wine Country Inn Palisade
777 Grande River Drive, Palisade, CO
Free Cancellation
Reserve now, pay when you stay
17.11 km from East Main Street
Stay at this 3.5-star business-friendly hotel in Palisade. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
Super 8 by Wyndham Grand Junction Colorado
728 Horizon Drive, Grand Junction, CO
4.83 km from East Main Street
Stay at this hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Super 8 by Wyndham Fruita
399 Jurassic Ave, I-70 Exit 19, Fruita, CO
18.54 km from East Main Street
Stay at this hotel in Fruita. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Studio 6 Grand Junction, CO
704 Horizon Dr, Grand Junction, CO
4.44 km from East Main Street
Book a stay at this business-friendly motel in Grand Junction. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
Comfort Inn & Suites
400 Jurassic Ave, Fruita, CO
18.57 km from East Main Street
Book a stay at this golf hotel in Fruita. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
La Quinta Inn & Suites by Wyndham Fruita
570 Raptor Rd, Fruita, CO
18.8 km from East Main Street
Stay at this 3-star business-friendly hotel in Fruita. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Doubletree Hotel Grand Junction
743 Horizon Dr, Grand Junction, CO
Free Cancellation
Reserve now, pay when you stay
4.98 km from East Main Street
Stay at this 4-star family-friendly hotel in Grand Junction. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff ...
Hotel Maverick
840 Kennedy Avenue, Grand Junction, CO
Free Cancellation
Reserve now, pay when you stay
1.57 km from East Main Street
Stay at this 4-star hotel in Grand Junction. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the helpful staff ...
Best Western Grande River Inn & Suites
3228 Interstate 70 Business Loop, Clifton, CO
Free Cancellation
Reserve now, pay when you stay
8.72 km from East Main Street
Stay at this hotel in Clifton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Red Roof Inn Grand Junction
2210 Hwy 6 and 50, Grand Junction, CO
Free Cancellation
Reserve now, pay when you stay
9.15 km from East Main Street
Stay at this hotel in Grand Junction. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
Tru by Hilton Grand Junction Downtown
243 Colorado Ave, Grand Junction, CO
Free Cancellation
Reserve now, pay when you stay
1.44 km from East Main Street
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and ...
Don't see what you're looking for?
See all available properties in East Main Street
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
East Main Street, Grand Junction Hotel Guide
Search for hotels in East Main Street on Expedia.com. You can easily find your hotels in East Main Street using one of the methods below:
- View our selection of featured hotels in East Main Street
- Use the map to find hotels in the East Main Street neighborhood you prefer
- Use the filters to see hotels in a specific area of East Main Street, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in East Main Street
- Enter your travel dates to view the best deals on hotels in East Main Street - while they last
More East Main Street Hotel Deals for Seniors and Members
- Grand Junction Vacation Rental w/ Fire Pit!
- Grand Vista Hotel
- La Quinta Inn & Suites by Wyndham Grand Junction
- Ramada by Wyndham Grand Junction
- Clarion Inn Grand Junction
- Wine Country Inn Palisade
- Super 8 by Wyndham Grand Junction Colorado
- Super 8 by Wyndham Fruita
- Studio 6 Grand Junction, CO
- Comfort Inn & Suites