Adults Only Resorts & Hotels in Missouri
Check availability on Missouri Adults Only Resorts & Hotels
Pick from 24 Missouri Adults Only Resorts & Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Westport Inn
Joplin
8.2 out of 10, Very Good, (711)
"A Great place to stay!"
Emmy
Historic Iron Horse Inn
Hermann
8.4 out of 10, Very Good, (21)
"Great small bed and breakfast. Nice room in a central location, it had a balcony overlooking the back yard. Nice place to eat your breakfast or have a glass of the local wine. Great location to walk around the town."
bettie
Moonrise Hotel
Delmar Loop
9.0 out of 10, Wonderful, (1929)
"This spot is our absolute favorite when visiting StL and stay every chance we get. The surrounding area is amazing and vibrant, the hotel is extremely friendly and inviting and the rooms are great and rich with city history! Can’t wait to get back. "
Brian
Chateau On The Lake Resort Spa and Convention Center
Skyview
8.4 out of 10, Very Good, (1384)
"The hotel was fabulous, we loved the Christmas decorations and our accommodations were excellent! "
Twila
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Missouri Hotel Reviews
Explore a world of travel with Expedia
Top destinations for Adults Only Resorts & Hotels in Missouri
More Hotel Options in Missouri
- Hotels with Air Conditioning in Missouri
- Hotels with WiFi in Missouri
- Family Hotels in Missouri
- Hotel with wifi in Missouri
- Hotels with a Pool in Missouri
- Hotels with Complimentary Breakfast in Missouri
- Smoke Free Hotels in Missouri
- Pet-friendly Hotels in Missouri
- Cheap Hotels in Missouri
- Hotels with Hot Tubs in Missouri
- Hotels with an Indoor Pool in Missouri
- Hotels with Bars in Missouri
- Luxury Hotels in Missouri
- Resorts & Hotels with Spas in Missouri
- Hotels with Balconies in Missouri
More Themes
- Hotels with Air Conditioning
- All-inclusive Hotel
- Hotels with Balconies
- Hotels with Bars
- Beach Hotels
- Boutique Hotels
- Cheap Hotels
- Business Hotels
- Casinos
- Hotel with a Concierge
- Hotels with Restaurants
- Family Hotels
- Hotels with Fireplaces
- Hotels with a Fitness Center
- Hotels with Free Airport Shuttle
- Hotels with Complimentary Breakfast
- Hotels with Free Parking
- Hotel with wifi
- Golf Hotels
- Historic Hotels
- Hotels with Hot Tubs
- Hotels with an Indoor Pool
- Apartment Hotel
- Hotels with a Kitchen
- Lakefront Hotels
- Hotels with a Lazy River
- Gay friendly Hotels
- Luxury Hotels
- Smoke Free Hotels
- Oceanfront Hotels
- Pet-friendly Hotels
- Hotels with a Pool
- Adventure Hotels
- Hotels on the River
- Romantic Hotels
- Hotels with Room Service
- Secluded Hotels
- Shopping Hotels
- Ski Hotels
- Hotels with smoking rooms
- Resorts & Hotels with Spas
- Hotels with Suites
- Green Hotels
- Hotels with Tennis Courts
- Waterpark Hotels
- Hotels with Waterslides
- Hotel Wedding Venues
- Hotels with WiFi
- Winery Hotels
Stay near popular Missouri attractions
- Hotels near St. Louis Union Station
- Hotels near Gateway Arch
- Hotels near Silver Dollar City
- Hotels near GEHA Field at Arrowhead Stadium
- Hotels near St. Louis Zoo
- Hotels near University of Missouri
- Hotels near Branson Landing
- Hotels near Table Rock Lake
- Hotels near Enterprise Center
- Hotels near Kansas City Convention Center
Discover hotels close to Missouri with room rates, reviews, and availability. Most hotels are fully refundable.
- Thousand Hills Resort Hotel
- Hyatt Vacation Club at The Lodges at Timber Ridge, Branson
- Loews Kansas City Hotel
- Pear Tree Inn St. Louis Airport
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- American Inn North Kansas City
- Orangewood Inn & Suites Kansas City Airport
- Hyatt Regency St. Louis at The Arch
- The Stone Castle Hotel & Conference Center
- Westgate Branson Woods Resort and Cabins