Vacations Close To Orlando Science Center

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Choose two or more items and save on your trip:

Orlando Science Center Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Destiny Palms Hotel Maingate West

Destiny Palms Hotel Maingate West

2.5 out of 5
Price was $463, price is now $329 per person
$329
per person
Oct 7 - Oct 13
found 5 hours ago
Roundtrip flight included
Detroit (DTW) to Orlando (MCO)

Margaritaville Cottages Orlando by Vstays with H2O Waterpark

Margaritaville Cottages Orlando by Vstays with H2O Waterpark

4 out of 5
Price was $2,076, price is now $938 per person
$938
per person
Oct 7 - Oct 13
found 5 hours ago
Roundtrip flight included
Detroit (DTW) to Orlando (MCO)

Seasons Florida Resort

Seasons Florida Resort

2 out of 5
Save 100% on your flight
Price was $681, price is now $347 per person
$347
per person
Oct 7 - Oct 13
found 5 hours ago
Roundtrip flight included
Detroit (DTW) to Orlando (MCO)

AC Hotel by Marriott Orlando Downtown

AC Hotel by Marriott Orlando Downtown

2.5 out of 5
Downtown Orlando
Save 100% on your flight
Price was $1,101, price is now $745 per person
$745
per person
Oct 7 - Oct 13
found 5 hours ago
Roundtrip flight included
Detroit (DTW) to Orlando (MCO)

Wyndham Grand Orlando Resort Bonnet Creek

Wyndham Grand Orlando Resort Bonnet Creek

4 out of 5
Save 100% on your flight
Price was $937, price is now $641 per person
$641
per person
Oct 7 - Oct 13
found 5 hours ago
Roundtrip flight included
Detroit (DTW) to Orlando (MCO)

Club Wyndham Bonnet Creek

Club Wyndham Bonnet Creek

3.5 out of 5
Save 100% on your flight
Price was $1,320, price is now $954 per person
$954
per person
Oct 7 - Oct 13
found 5 hours ago
Roundtrip flight included
Detroit (DTW) to Orlando (MCO)
When staying at a hotel, I always look at the quality of the bed, the service, the pool, and the cleanliness. This hotel exceeded all my expectations. The bed was comfortable, and the linens were spotless. The cleanliness was impeccable, as was the staff service. I have no complaints whatsoever. I will definitely be back.

Reviewed on Sep 1, 2026

The Irlo

The Irlo

3 out of 5
Price was $536, price is now $390 per person
$390
per person
Oct 7 - Oct 13
found 5 hours ago
Roundtrip flight included
Detroit (DTW) to Orlando (MCO)
Clean, cozy and equipped with everything for comfortable stay! We loved it!

Reviewed on Sep 1, 2026

Universal's Cabana Bay Beach Resort

Universal's Cabana Bay Beach Resort

3.5 out of 5
Florida Center
Save 100% on your flight
Price was $1,019, price is now $742 per person
$742
per person
Oct 7 - Oct 13
found 5 hours ago
Roundtrip flight included
Detroit (DTW) to Orlando (MCO)
We had an excellent stay. This resort had everything you and your family may need.

Reviewed on Sep 1, 2026

Don't see what you're looking for?
See all available trips from Columbus to Orlando Science Center
View all trips

Best Lodging Options Near Orlando Science Center

Comfort Suites Downtown

Comfort Suites Downtown

2.5 out of 5
2416 North Orange Avenue Orlando FL
0.47 km from Orlando Science Center
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Courtyard by Marriott Orlando Downtown

Courtyard by Marriott Orlando Downtown

3 out of 5
730 N Magnolia Ave Orlando FL
2.21 km from Orlando Science Center
Book a stay at this business-friendly hotel in Orlando. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
DoubleTree by Hilton Hotel Orlando Downtown

DoubleTree by Hilton Hotel Orlando Downtown

4 out of 5
60 South Ivanhoe Boulevard Orlando FL
1.81 km from Orlando Science Center
Book a stay at this business-friendly hotel in Orlando. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and ...
Residence Inn by Marriott Orlando Downtown

Residence Inn by Marriott Orlando Downtown

3 out of 5
680 North Orange Avenue Orlando FL
2.43 km from Orlando Science Center
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean ...
Crowne Plaza Orlando - Downtown by IHG

Crowne Plaza Orlando - Downtown by IHG

3.5 out of 5
304 W Colonial Drive Orlando FL
2.68 km from Orlando Science Center
Book a stay at this business-friendly hotel in Orlando. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
Hilton Garden Inn Orlando Downtown

Hilton Garden Inn Orlando Downtown

3 out of 5
401 North Magnolia Avenue Orlando FL
2.83 km from Orlando Science Center
Book a stay at this business-friendly hotel in Orlando. Enjoy breakfast (surcharge), a fitness center, and valet parking (surcharge). Our guests praise the helpful ...
Home2 Suites by Hilton Orlando Downtown

Home2 Suites by Hilton Orlando Downtown

2.5 out of 5
401 North Magnolia Avenue Orlando FL
2.82 km from Orlando Science Center
Stay at this hotel in Orlando. Enjoy free breakfast, a rooftop terrace, and a fitness center. Our guests praise the helpful staff and the clean rooms in our ...
The Eo Inn - Downtown

The Eo Inn - Downtown

3 out of 5
227 N Eola Drive Orlando FL
2.96 km from Orlando Science Center
Stay at this hotel in Orlando. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Don't see what you're looking for?
See all available properties in Orlando Science Center
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.