Business Hotels in Big Spring 2026
Featured Big Spring Business Hotels
Hotel Settles
200 East 3rd Street Big Spring TX
Fully refundableReserve now, pay when you stay
Quality Inn & Suites Big Spring
917 Lamesa Hwy Big Spring TX
Best Western Palace Inn & Suites
915 Lamesa Highway Big Spring TX
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Hampton Inn & Suites Big Spring
805 Interstate 20 Frontage Rd. Big Spring TX
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Comfort Inn & Suites
1109 N Aylesford St Big Spring TX
Knights Inn Big Spring
1000 W 4th St Big Spring TX
Fully refundableReserve now, pay when you stay
La Quinta Inn & Suites by Wyndham Big Spring
1102 I-20 Big Spring TX
Towneplace Suites Big Spring
1011 N San Antonio St Big Spring TX
Fully refundableReserve now, pay when you stay
Eagle's Den Suites Big Spring a Travelodge by Wyndham
901 E Interstate 20 Big Spring TX
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.