2026 4 Star Hotels in South Eastern Region

Choose two or more items and save on your trip:

Featured South Eastern Region 4 Star Hotels

The Embassy Valletta Hotel

The Embassy Valletta Hotel

4.5 out of 5
Strait street 173 Valletta
The Embassy Valletta Hotel
Palais Le Brun

Palais Le Brun

4.5 out of 5
101 old bakery street Valletta
Fully refundableReserve now, pay when you stay
Palais Le Brun
The Barrister

The Barrister

4 out of 5
57, St. Christopher Street Valletta
The Barrister
19 Rooms

19 Rooms

4 out of 5
87 Saint Christopher Street Valletta
19 Rooms
The Gomerino Hotel

The Gomerino Hotel

4 out of 5
247 St Paul St Valletta
Fully refundableReserve now, pay when you stay
The Gomerino Hotel
San Karlu Hotel

San Karlu Hotel

4 out of 5
28 Saint Charles Street Valletta South Eastern Region
Fully refundableReserve now, pay when you stay
San Karlu Hotel
Mulberry Suites by The LVH Collection

Mulberry Suites by The LVH Collection

4 out of 5
31 Old Bakery St Valletta
Mulberry Suites by The LVH Collection
SU29 Boutique Hotel

SU29 Boutique Hotel

4.5 out of 5
29, St. Ursula Steps Valletta
SU29 Boutique Hotel
66 Saint Pauls & Spa

66 Saint Pauls & Spa

4.5 out of 5
66 St. Pauls Street Valletta
66 Saint Pauls & Spa
See all 1,049 properties in South Eastern Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.