2026 4 Star Hotels in Prague 2

Choose two or more items and save on your trip:

Featured Prague 2 4 Star Hotels

Mosaic House Design Hotel

Mosaic House Design Hotel

4 out of 5
Odboru 4 Prague
Mosaic House Design Hotel
Hotel Unique

Hotel Unique

4 out of 5
Uruguayská 540/20 Prague
Hotel Unique
Novotel Praha Wenceslas Square

Novotel Praha Wenceslas Square

4 out of 5
Katerinska 38 Prague
Fully refundableReserve now, pay when you stay
Novotel Praha Wenceslas Square
Hermitage Hotel Prague

Hermitage Hotel Prague

4.5 out of 5
Svobodova 1961/1 Prague
Hermitage Hotel Prague
EA Hotel New Town

EA Hotel New Town

4 out of 5
Zitna 525/28 Prague
Fully refundableReserve now, pay when you stay
EA Hotel New Town
Hotel Ambiance

Hotel Ambiance

4 out of 5
Tyrsova 1841/8 Prague
Hotel Ambiance
Residence Jecna

Residence Jecna

4 out of 5
Jecná 1635/35 Prague
Residence Jecna
Aparthotel Rimska 14

Aparthotel Rimska 14

4 out of 5
Rimska 104/14 Prague
Aparthotel Rimska 14
Mamaison Residence Downtown Prague

Mamaison Residence Downtown Prague

4 out of 5
Na Rybnicku 5 Prague
Mamaison Residence Downtown Prague
See all 408 properties in Prague 2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.