2026 4 Star Hotels in Lyon City Centre

Choose two or more items and save on your trip:

Featured Lyon City Centre 4 Star Hotels

Radisson Blu Hotel Lyon

Radisson Blu Hotel Lyon

4 out of 5
129 rue Servient Lyon Rhone
Fully refundableReserve now, pay when you stay
Radisson Blu Hotel Lyon
Mercure Lyon Centre Saxe Lafayette

Mercure Lyon Centre Saxe Lafayette

4 out of 5
29 Rue De Bonnel Lyon Rhone
Fully refundableReserve now, pay when you stay
Mercure Lyon Centre Saxe Lafayette
Mercure Lyon Centre Château Perrache

Mercure Lyon Centre Château Perrache

4 out of 5
12 Cours De Verdun Rambaud Lyon Rhone
Fully refundableReserve now, pay when you stay
Mercure Lyon Centre Château Perrache
Bikube Coliving Hôtel - Lyon Centre Lumière

Bikube Coliving Hôtel - Lyon Centre Lumière

4 out of 5
9 Rue Saint-Théodore Lyon Rhône
Fully refundableReserve now, pay when you stay
Bikube Coliving Hôtel - Lyon Centre Lumière
Grand Hotel Des Terreaux

Grand Hotel Des Terreaux

4 out of 5
16 Rue Lanterne Lyon Rhone
Grand Hotel Des Terreaux
Keystone Hotel & Spa Lyon - Handwritten Collection

Keystone Hotel & Spa Lyon - Handwritten Collection

4 out of 5
15 Rue Casimir Périer Lyon Rhône
Fully refundableReserve now, pay when you stay
Keystone Hotel & Spa Lyon - Handwritten Collection
Globe et Cecil Hôtel

Globe et Cecil Hôtel

4 out of 5
21 Rue Gasparin Lyon Rhone
Fully refundableReserve now, pay when you stay
Globe et Cecil Hôtel
Pullman Lyon

Pullman Lyon

4 out of 5
14 place Charles Béraudier Lyon
Fully refundableReserve now, pay when you stay
Pullman Lyon
Le Phenix Hotel

Le Phenix Hotel

4 out of 5
7 Quai De Bondy Lyon Rhone
Fully refundableReserve now, pay when you stay
Le Phenix Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.