2026 4 Star Hotels in Lyon City Centre

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Featured Lyon City Centre 4 Star Hotels

Radisson Blu Hotel Lyon

Radisson Blu Hotel Lyon

4 out of 5
129 rue Servient Lyon Rhone
Fully refundableReserve now, pay when you stay
Radisson Blu Hotel Lyon
Bikube Coliving Hôtel - Lyon Centre Lumière

Bikube Coliving Hôtel - Lyon Centre Lumière

4 out of 5
9 Rue Saint-Théodore Lyon Rhône
Fully refundableReserve now, pay when you stay
Bikube Coliving Hôtel - Lyon Centre Lumière
Globe et Cecil Hôtel

Globe et Cecil Hôtel

4 out of 5
21 Rue Gasparin Lyon Rhone
Fully refundableReserve now, pay when you stay
Globe et Cecil Hôtel
Hotel Silky by HappyCulture

Hotel Silky by HappyCulture

4 out of 5
2 Place Francisque Regaud Lyon Rhone
Fully refundableReserve now, pay when you stay
Hotel Silky by HappyCulture
Keystone Hôtel & Spa

Keystone Hôtel & Spa

4 out of 5
15 Rue Casimir Périer Lyon Rhône
Fully refundableReserve now, pay when you stay
Keystone Hôtel & Spa
Pullman Lyon

Pullman Lyon

4 out of 5
14 place Charles Béraudier Lyon
Fully refundableReserve now, pay when you stay
Pullman Lyon
Hôtel Mercure Lyon Centre - Gare Part Dieu

Hôtel Mercure Lyon Centre - Gare Part Dieu

4 out of 5
50 Rue De La Villette Lyon Rhone
Fully refundableReserve now, pay when you stay
Hôtel Mercure Lyon Centre - Gare Part Dieu
Carlton Hotel Lyon - MGallery Collection

Carlton Hotel Lyon - MGallery Collection

4 out of 5
4 Rue De Jussieu Lyon Rhone
Fully refundableReserve now, pay when you stay
Carlton Hotel Lyon - MGallery Collection
Mercure Lyon Centre Château Perrache

Mercure Lyon Centre Château Perrache

4 out of 5
12 Cours De Verdun Rambaud Lyon Rhone
Fully refundableReserve now, pay when you stay
Mercure Lyon Centre Château Perrache
See all 798 properties in Lyon City Centre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.