2026 4 Star Hotels in Lyon City Centre

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Featured Lyon City Centre 4 Star Hotels

Mercure Lyon Centre Château Perrache

Mercure Lyon Centre Château Perrache

4 out of 5
12 Cours De Verdun Rambaud Lyon Rhone
Fully refundableReserve now, pay when you stay
Mercure Lyon Centre Château Perrache
Globe et Cecil Hôtel

Globe et Cecil Hôtel

4 out of 5
21 Rue Gasparin Lyon Rhone
Fully refundableReserve now, pay when you stay
Globe et Cecil Hôtel
Bikube Lyon

Bikube Lyon

4 out of 5
9 Rue Saint-Théodore Lyon Rhône
Fully refundableReserve now, pay when you stay
Bikube Lyon
Radisson Blu Hotel Lyon

Radisson Blu Hotel Lyon

4 out of 5
129 rue Servient Lyon Rhone
Fully refundableReserve now, pay when you stay
Radisson Blu Hotel Lyon
OKKO Hotels Lyon Centre

OKKO Hotels Lyon Centre

4 out of 5
14 bis, quai General Sarrail Lyon Rhone
Fully refundableReserve now, pay when you stay
OKKO Hotels Lyon Centre
Hotel Silky by HappyCulture

Hotel Silky by HappyCulture

4 out of 5
2 Place Francisque Regaud Lyon Rhone
Fully refundableReserve now, pay when you stay
Hotel Silky by HappyCulture
Q7 Lodge Lyon 7

Q7 Lodge Lyon 7

4 out of 5
7 rue Félix Brun Lyon Rhone
Fully refundableReserve now, pay when you stay
Q7 Lodge Lyon 7
Pullman Lyon

Pullman Lyon

4 out of 5
14 place Charles Béraudier Lyon
Fully refundableReserve now, pay when you stay
Pullman Lyon
Le Phenix Hotel

Le Phenix Hotel

4 out of 5
7 Quai De Bondy Lyon Rhone
Fully refundableReserve now, pay when you stay
Le Phenix Hotel
See all 770 properties in Lyon City Centre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.