2026 4 Star Hotels in Lyon City Centre

Choose two or more items and save on your trip:

Featured Lyon City Centre 4 Star Hotels

Radisson Blu Hotel Lyon

Radisson Blu Hotel Lyon

4 out of 5
129 rue Servient Lyon Rhone
Fully refundableReserve now, pay when you stay
Radisson Blu Hotel Lyon
Hôtel Mercure Lyon Centre - Gare Part Dieu

Hôtel Mercure Lyon Centre - Gare Part Dieu

4 out of 5
50 Rue De La Villette Lyon Rhone
Fully refundableReserve now, pay when you stay
Hôtel Mercure Lyon Centre - Gare Part Dieu
Mercure Lyon Centre Château Perrache

Mercure Lyon Centre Château Perrache

4 out of 5
12 Cours De Verdun Rambaud Lyon Rhone
Mercure Lyon Centre Château Perrache
Grand Hotel Des Terreaux

Grand Hotel Des Terreaux

4 out of 5
16 Rue Lanterne Lyon Rhone
Grand Hotel Des Terreaux
Globe et Cecil Hôtel

Globe et Cecil Hôtel

4 out of 5
21 Rue Gasparin Lyon Rhone
Globe et Cecil Hôtel
Bikube Coliving Hôtel - Lyon Centre Lumière

Bikube Coliving Hôtel - Lyon Centre Lumière

4 out of 5
9 Rue Saint-Théodore Lyon Rhône
Bikube Coliving Hôtel - Lyon Centre Lumière
Hôtel Le Roosevelt

Hôtel Le Roosevelt

4 out of 5
48 Rue De Seze Lyon Rhone
Fully refundableReserve now, pay when you stay
Hôtel Le Roosevelt
Le Phenix Hotel

Le Phenix Hotel

4 out of 5
7 Quai De Bondy Lyon Rhone
Fully refundableReserve now, pay when you stay
Le Phenix Hotel
Mercure Lyon Centre Saxe Lafayette

Mercure Lyon Centre Saxe Lafayette

4 out of 5
29 Rue De Bonnel Lyon Rhone
Fully refundableReserve now, pay when you stay
Mercure Lyon Centre Saxe Lafayette
See all 781 properties in Lyon City Centre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.