2025 4 Star Hotels in Downtown San Diego

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Featured Downtown San Diego 4 Star Hotels

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
Wyndham San Diego Bayside
Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter

4 out of 5
830 Sixth Avenue, San Diego, CA
Fully refundableReserve now, pay when you stay
Palihotel San Diego Gaslamp Quarter
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
Manchester Grand Hyatt San Diego
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave, San Diego, CA
Fully refundableReserve now, pay when you stay
Hard Rock Hotel San Diego
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown

4 out of 5
601 Pacific Hwy, San Diego, CA
Fully refundableReserve now, pay when you stay
Embassy Suites by Hilton San Diego Bay Downtown
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

4 out of 5
675 L St, San Diego, CA
Fully refundableReserve now, pay when you stay
Omni San Diego Hotel at the Ballpark
The Little Italy Hotel Downtown San Diego

The Little Italy Hotel Downtown San Diego

4 out of 5
1646 Front St, San Diego, CA
Fully refundableReserve now, pay when you stay
The Little Italy Hotel Downtown San Diego
The Westin San Diego Bayview

The Westin San Diego Bayview

4 out of 5
1051 Columbia street, San Diego, CA
Fully refundableReserve now, pay when you stay
The Westin San Diego Bayview
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4 out of 5
333 W Harbor Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
Marriott Marquis San Diego Marina
See all 796 properties in Downtown San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.