2026 4 Star Hotels in Downtown San Diego

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Featured Downtown San Diego 4 Star Hotels

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Wyndham San Diego Bayside
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
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Hard Rock Hotel San Diego
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
Fully refundableReserve now, pay when you stay
Manchester Grand Hyatt San Diego
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4 out of 5
333 W Harbor Dr San Diego CA
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Marriott Marquis San Diego Marina
San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter

4 out of 5
660 K St San Diego CA
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San Diego Marriott Gaslamp Quarter
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

4 out of 5
675 L St San Diego CA
Fully refundableReserve now, pay when you stay
Omni San Diego Hotel at the Ballpark
The Westin San Diego Gaslamp Quarter

The Westin San Diego Gaslamp Quarter

4 out of 5
910 Broadway Circle San Diego CA
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The Westin San Diego Gaslamp Quarter
Hilton San Diego Gaslamp Quarter

Hilton San Diego Gaslamp Quarter

4 out of 5
401 K St San Diego CA
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Hilton San Diego Gaslamp Quarter
Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter

4 out of 5
830 Sixth Avenue San Diego CA
Fully refundableReserve now, pay when you stay
Palihotel San Diego Gaslamp Quarter
See all 893 properties in Downtown San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.