Flights from Buffalo to Knoxville

Cheapest flights from Buffalo

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Jul 4 - Wed, Jul 9

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$300 Roundtrip, found 3 days ago

$300

Roundtrip

found 3 days ago

Select Delta flight, departing Fri, Jul 4 from Buffalo Niagara Intl. to Des Moines Intl., returning Wed, Jul 9, priced at $300 found 3 days ago

Wed, Jul 9 - Wed, Jul 9

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$303 Roundtrip, found 3 days ago

$303

Roundtrip

found 3 days ago

Select Delta flight, departing Wed, Jul 9 from Buffalo Niagara Intl. to Des Moines Intl., returning Wed, Jul 9, priced at $303 found 3 days ago

Fri, Jul 4 - Sat, Jul 12

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$332 Roundtrip, found 3 days ago

$332

Roundtrip

found 3 days ago

Select Delta flight, departing Fri, Jul 4 from Buffalo Niagara Intl. to Des Moines Intl., returning Sat, Jul 12, priced at $332 found 3 days ago

Wed, Jul 9 - Mon, Jul 14

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$335 Roundtrip, found 6 days ago

$335

Roundtrip

found 6 days ago

Select United flight, departing Wed, Jul 9 from Buffalo Niagara Intl. to Des Moines Intl., returning Mon, Jul 14, priced at $335 found 6 days ago

Wed, Jul 9 - Mon, Jul 14

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$335 Roundtrip, found 6 days ago

$335

Roundtrip

found 6 days ago

Select American Airlines flight, departing Wed, Jul 9 from Buffalo Niagara Intl. to Des Moines Intl., returning Mon, Jul 14, priced at $335 found 6 days ago

Wed, Jul 9 - Mon, Jul 14

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$340 Roundtrip, found 6 days ago

$340

Roundtrip

found 6 days ago

Select United flight, departing Wed, Jul 9 from Buffalo Niagara Intl. to Des Moines Intl., returning Mon, Jul 14, priced at $340 found 6 days ago

Wed, Jul 9 - Mon, Jul 14

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$352 Roundtrip, found 6 days ago

$352

Roundtrip

found 6 days ago

Select United flight, departing Wed, Jul 9 from Buffalo Niagara Intl. to Des Moines Intl., returning Mon, Jul 14, priced at $352 found 6 days ago

Tue, Jul 8 - Wed, Jul 9

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$361 Roundtrip, found 3 days ago

$361

Roundtrip

found 3 days ago

Select Delta flight, departing Tue, Jul 8 from Buffalo Niagara Intl. to Des Moines Intl., returning Wed, Jul 9, priced at $361 found 3 days ago

Fri, Jul 4 - Thu, Jul 10

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$362 Roundtrip, found 3 days ago

$362

Roundtrip

found 3 days ago

Select Delta flight, departing Fri, Jul 4 from Buffalo Niagara Intl. to Des Moines Intl., returning Thu, Jul 10, priced at $362 found 3 days ago

Thu, Jul 10 - Sat, Jul 12

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$367 Roundtrip, found 3 days ago

$367

Roundtrip

found 3 days ago

Select Delta flight, departing Thu, Jul 10 from Buffalo Niagara Intl. to Des Moines Intl., returning Sat, Jul 12, priced at $367 found 3 days ago

Fri, Jul 4 - Sun, Jul 13

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$368 Roundtrip, found 3 days ago

$368

Roundtrip

found 3 days ago

Select Delta flight, departing Fri, Jul 4 from Buffalo Niagara Intl. to Des Moines Intl., returning Sun, Jul 13, priced at $368 found 3 days ago

Wed, Jul 9 - Mon, Jul 14

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$370 Roundtrip, found 6 days ago

$370

Roundtrip

found 6 days ago

Select United flight, departing Wed, Jul 9 from Buffalo Niagara Intl. to Des Moines Intl., returning Mon, Jul 14, priced at $370 found 6 days ago

Wed, Jul 9 - Sun, Jul 13

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$371 Roundtrip, found 3 days ago

$371

Roundtrip

found 3 days ago

Select Delta flight, departing Wed, Jul 9 from Buffalo Niagara Intl. to Des Moines Intl., returning Sun, Jul 13, priced at $371 found 3 days ago

Mon, Jul 7 - Fri, Jul 11

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$372 Roundtrip, found 3 days ago

$372

Roundtrip

found 3 days ago

Select United flight, departing Mon, Jul 7 from Buffalo Niagara Intl. to Des Moines Intl., returning Fri, Jul 11, priced at $372 found 3 days ago

Wed, Jul 9 - Mon, Jul 14

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$379 Roundtrip, found 6 days ago

$379

Roundtrip

found 6 days ago

Select United flight, departing Wed, Jul 9 from Buffalo Niagara Intl. to Des Moines Intl., returning Mon, Jul 14, priced at $379 found 6 days ago

Mon, Jul 7 - Fri, Jul 11

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$387 Roundtrip, found 3 days ago

$387

Roundtrip

found 3 days ago

Select American Airlines flight, departing Mon, Jul 7 from Buffalo Niagara Intl. to Des Moines Intl., returning Fri, Jul 11, priced at $387 found 3 days ago

Wed, Jul 9 - Mon, Jul 14

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$389 Roundtrip, found 6 days ago

$389

Roundtrip

found 6 days ago

Select American Airlines flight, departing Wed, Jul 9 from Buffalo Niagara Intl. to Des Moines Intl., returning Mon, Jul 14, priced at $389 found 6 days ago

Tue, Jul 8 - Fri, Jul 11

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$393 Roundtrip, found 3 days ago

$393

Roundtrip

found 3 days ago

Select Delta flight, departing Tue, Jul 8 from Buffalo Niagara Intl. to Des Moines Intl., returning Fri, Jul 11, priced at $393 found 3 days ago

Wed, Jul 9 - Mon, Jul 14

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$395 Roundtrip, found 6 days ago

$395

Roundtrip

found 6 days ago

Select American Airlines flight, departing Wed, Jul 9 from Buffalo Niagara Intl. to Des Moines Intl., returning Mon, Jul 14, priced at $395 found 6 days ago

Wed, Jul 9 - Mon, Jul 14

BUF

Buffalo Niagara Intl.

DSM

Des Moines Intl.

$400 Roundtrip, found 6 days ago

$400

Roundtrip

found 6 days ago

Select Delta flight, departing Wed, Jul 9 from Buffalo Niagara Intl. to Des Moines Intl., returning Mon, Jul 14, priced at $400 found 6 days ago