Flights from St. Louis to Des Moines

Cheapest flights from St. Louis

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Jul 22 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$320 Roundtrip, found 22 hours ago

$320

Roundtrip

found 22 hours ago

Select Delta flight, departing Tue, Jul 22 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $320 found 22 hours ago

Tue, Jul 22 - Fri, Jul 25

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$331 Roundtrip, found 22 hours ago

$331

Roundtrip

found 22 hours ago

Select Delta flight, departing Tue, Jul 22 from Lambert-St. Louis Intl. to Des Moines Intl., returning Fri, Jul 25, priced at $331 found 22 hours ago

Thu, Jul 24 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$338 Roundtrip, found 22 hours ago

$338

Roundtrip

found 22 hours ago

Select United flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $338 found 22 hours ago

Thu, Jul 24 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$340 Roundtrip, found 22 hours ago

$340

Roundtrip

found 22 hours ago

Select American Airlines flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $340 found 22 hours ago

Thu, Jul 24 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$350 Roundtrip, found 22 hours ago

$350

Roundtrip

found 22 hours ago

Select United flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $350 found 22 hours ago

Thu, Jul 24 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$351 Roundtrip, found 22 hours ago

$351

Roundtrip

found 22 hours ago

Select United flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $351 found 22 hours ago

Tue, Jul 22 - Sat, Jul 26

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$362 Roundtrip, found 22 hours ago

$362

Roundtrip

found 22 hours ago

Select Delta flight, departing Tue, Jul 22 from Lambert-St. Louis Intl. to Des Moines Intl., returning Sat, Jul 26, priced at $362 found 22 hours ago

Thu, Jul 24 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$368 Roundtrip, found 22 hours ago

$368

Roundtrip

found 22 hours ago

Select United flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $368 found 22 hours ago

Thu, Jul 24 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$370 Roundtrip, found 22 hours ago

$370

Roundtrip

found 22 hours ago

Select American Airlines flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $370 found 22 hours ago

Thu, Jul 24 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$371 Roundtrip, found 22 hours ago

$371

Roundtrip

found 22 hours ago

Select American Airlines flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $371 found 22 hours ago

Thu, Jul 24 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$379 Roundtrip, found 22 hours ago

$379

Roundtrip

found 22 hours ago

Select United flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $379 found 22 hours ago

Thu, Jul 24 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$381 Roundtrip, found 22 hours ago

$381

Roundtrip

found 22 hours ago

Select United flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $381 found 22 hours ago

Thu, Jul 24 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$390 Roundtrip, found 22 hours ago

$390

Roundtrip

found 22 hours ago

Select United flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $390 found 22 hours ago

Fri, Jul 25 - Sat, Jul 26

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$391 Roundtrip, found 22 hours ago

$391

Roundtrip

found 22 hours ago

Select American Airlines flight, departing Fri, Jul 25 from Lambert-St. Louis Intl. to Des Moines Intl., returning Sat, Jul 26, priced at $391 found 22 hours ago

Thu, Jul 24 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$392 Roundtrip, found 22 hours ago

$392

Roundtrip

found 22 hours ago

Select United flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $392 found 22 hours ago

Thu, Jul 24 - Sat, Jul 26

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$393 Roundtrip, found 22 hours ago

$393

Roundtrip

found 22 hours ago

Select Delta flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Sat, Jul 26, priced at $393 found 22 hours ago

Thu, Jul 24 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$394 Roundtrip, found 22 hours ago

$394

Roundtrip

found 22 hours ago

Select American Airlines flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $394 found 22 hours ago

Thu, Jul 24 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$396 Roundtrip, found 22 hours ago

$396

Roundtrip

found 22 hours ago

Select Southern Airways Express flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $396 found 22 hours ago

Thu, Jul 24 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$398 Roundtrip, found 22 hours ago

$398

Roundtrip

found 22 hours ago

Select United flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $398 found 22 hours ago

Thu, Jul 24 - Mon, Jul 28

STL

Lambert-St. Louis Intl.

DSM

Des Moines Intl.

$400 Roundtrip, found 22 hours ago

$400

Roundtrip

found 22 hours ago

Select American Airlines flight, departing Thu, Jul 24 from Lambert-St. Louis Intl. to Des Moines Intl., returning Mon, Jul 28, priced at $400 found 22 hours ago