Flights from Detroit to St. Charles

Cheapest flights from Detroit

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Jun 27 - Sun, Jun 29

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$96 Roundtrip, found 1 day ago

$96

Roundtrip

found 1 day ago

Select Spirit Airlines flight, departing Fri, Jun 27 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Sun, Jun 29, priced at $96 found 1 day ago

Fri, Jun 27 - Fri, Jun 27

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$127 Roundtrip, found 1 day ago

$127

Roundtrip

found 1 day ago

Select Spirit Airlines flight, departing Fri, Jun 27 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Fri, Jun 27, priced at $127 found 1 day ago

Thu, Jun 26 - Mon, Jun 30

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$135 Roundtrip, found 1 day ago

$135

Roundtrip

found 1 day ago

Select Spirit Airlines flight, departing Thu, Jun 26 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Mon, Jun 30, priced at $135 found 1 day ago

Mon, Jun 23 - Fri, Jun 27

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$148 Roundtrip, found 1 day ago

$148

Roundtrip

found 1 day ago

Select Spirit Airlines flight, departing Mon, Jun 23 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Fri, Jun 27, priced at $148 found 1 day ago

Thu, Jun 26 - Mon, Jun 30

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$174 Roundtrip, found 1 day ago

$174

Roundtrip

found 1 day ago

Select Frontier Airlines flight, departing Thu, Jun 26 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Mon, Jun 30, priced at $174 found 1 day ago

Fri, Jun 27 - Thu, Jul 3

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$181 Roundtrip, found 1 day ago

$181

Roundtrip

found 1 day ago

Select Delta flight, departing Fri, Jun 27 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Thu, Jul 3, priced at $181 found 1 day ago

Thu, Jun 26 - Mon, Jun 30

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$186 Roundtrip, found 1 day ago

$186

Roundtrip

found 1 day ago

Select Spirit Airlines flight, departing Thu, Jun 26 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Mon, Jun 30, priced at $186 found 1 day ago

Thu, Jun 26 - Mon, Jun 30

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$205 Roundtrip, found 1 day ago

$205

Roundtrip

found 1 day ago

Select Spirit Airlines flight, departing Thu, Jun 26 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Mon, Jun 30, priced at $205 found 1 day ago

Thu, Jun 26 - Mon, Jun 30

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$221 Roundtrip, found 1 day ago

$221

Roundtrip

found 1 day ago

Select Spirit Airlines flight, departing Thu, Jun 26 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Mon, Jun 30, priced at $221 found 1 day ago

Thu, Jun 26 - Mon, Jun 30

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$225 Roundtrip, found 1 day ago

$225

Roundtrip

found 1 day ago

Select Spirit Airlines flight, departing Thu, Jun 26 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Mon, Jun 30, priced at $225 found 1 day ago

Thu, Jun 26 - Mon, Jun 30

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$231 Roundtrip, found 1 day ago

$231

Roundtrip

found 1 day ago

Select Spirit Airlines flight, departing Thu, Jun 26 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Mon, Jun 30, priced at $231 found 1 day ago

Fri, Jun 27 - Mon, Jun 30

FNT

Bishop Intl.

STL

Lambert-St. Louis Intl.

$239 Roundtrip, found 1 day ago

$239

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jun 27 from Bishop Intl. to Lambert-St. Louis Intl., returning Mon, Jun 30, priced at $239 found 1 day ago

Fri, Jun 27 - Mon, Jun 30

FNT

Bishop Intl.

STL

Lambert-St. Louis Intl.

$239 Roundtrip, found 1 day ago

$239

Roundtrip

found 1 day ago

Select American Airlines flight, departing Fri, Jun 27 from Bishop Intl. to Lambert-St. Louis Intl., returning Mon, Jun 30, priced at $239 found 1 day ago

Mon, Jun 23 - Thu, Jul 3

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$260 Roundtrip, found 1 day ago

$260

Roundtrip

found 1 day ago

Select Spirit Airlines flight, departing Mon, Jun 23 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Thu, Jul 3, priced at $260 found 1 day ago

Thu, Jun 26 - Mon, Jun 30

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$283 Roundtrip, found 1 day ago

$283

Roundtrip

found 1 day ago

Select Spirit Airlines flight, departing Thu, Jun 26 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Mon, Jun 30, priced at $283 found 1 day ago

Thu, Jun 26 - Mon, Jun 30

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$285 Roundtrip, found 1 day ago

$285

Roundtrip

found 1 day ago

Select Spirit Airlines flight, departing Thu, Jun 26 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Mon, Jun 30, priced at $285 found 1 day ago

Thu, Jun 26 - Tue, Jul 1

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$287 Roundtrip, found 1 day ago

$287

Roundtrip

found 1 day ago

Select Frontier Airlines flight, departing Thu, Jun 26 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Tue, Jul 1, priced at $287 found 1 day ago

Sat, Jun 28 - Sun, Jun 29

FNT

Bishop Intl.

STL

Lambert-St. Louis Intl.

$299 Roundtrip, found 1 day ago

$299

Roundtrip

found 1 day ago

Select American Airlines flight, departing Sat, Jun 28 from Bishop Intl. to Lambert-St. Louis Intl., returning Sun, Jun 29, priced at $299 found 1 day ago

Sat, Jun 28 - Sat, Jun 28

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$299 Roundtrip, found 1 day ago

$299

Roundtrip

found 1 day ago

Select Delta flight, departing Sat, Jun 28 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Sat, Jun 28, priced at $299 found 1 day ago

Thu, Jun 26 - Mon, Jun 30

DTW

Detroit Metropolitan Wayne County

STL

Lambert-St. Louis Intl.

$310 Roundtrip, found 1 day ago

$310

Roundtrip

found 1 day ago

Select Delta flight, departing Thu, Jun 26 from Detroit Metropolitan Wayne County to Lambert-St. Louis Intl., returning Mon, Jun 30, priced at $310 found 1 day ago