Flights from Detroit to Simpsonville

Cheapest flights from Detroit

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Sep 3 - Tue, Sep 9

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$335 Roundtrip, found 3 days ago

$335

Roundtrip

found 3 days ago

Select Delta flight, departing Wed, Sep 3 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Tue, Sep 9, priced at $335 found 3 days ago

Fri, Sep 5 - Mon, Sep 8

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$350 Roundtrip, found 3 days ago

$350

Roundtrip

found 3 days ago

Select American Airlines flight, departing Fri, Sep 5 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $350 found 3 days ago

Fri, Sep 5 - Mon, Sep 8

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$351 Roundtrip, found 3 days ago

$351

Roundtrip

found 3 days ago

Select American Airlines flight, departing Fri, Sep 5 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $351 found 3 days ago

Wed, Sep 3 - Sat, Sep 6

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$367 Roundtrip, found 3 days ago

$367

Roundtrip

found 3 days ago

Select Delta flight, departing Wed, Sep 3 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Sat, Sep 6, priced at $367 found 3 days ago

Fri, Sep 5 - Mon, Sep 8

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$387 Roundtrip, found 3 days ago

$387

Roundtrip

found 3 days ago

Select Delta flight, departing Fri, Sep 5 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $387 found 3 days ago

Fri, Sep 5 - Mon, Sep 8

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$396 Roundtrip, found 3 days ago

$396

Roundtrip

found 3 days ago

Select American Airlines flight, departing Fri, Sep 5 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $396 found 3 days ago

Fri, Sep 5 - Mon, Sep 8

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$397 Roundtrip, found 3 days ago

$397

Roundtrip

found 3 days ago

Select Delta flight, departing Fri, Sep 5 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $397 found 3 days ago

Sat, Sep 6 - Wed, Sep 10

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$398 Roundtrip, found 3 days ago

$398

Roundtrip

found 3 days ago

Select United flight, departing Sat, Sep 6 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Wed, Sep 10, priced at $398 found 3 days ago

Tue, Sep 2 - Sat, Sep 6

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$399 Roundtrip, found 3 days ago

$399

Roundtrip

found 3 days ago

Select Delta flight, departing Tue, Sep 2 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Sat, Sep 6, priced at $399 found 3 days ago

Fri, Sep 5 - Mon, Sep 8

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$407 Roundtrip, found 3 days ago

$407

Roundtrip

found 3 days ago

Select American Airlines flight, departing Fri, Sep 5 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $407 found 3 days ago

Fri, Sep 5 - Mon, Sep 8

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$409 Roundtrip, found 3 days ago

$409

Roundtrip

found 3 days ago

Select Delta flight, departing Fri, Sep 5 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $409 found 3 days ago

Fri, Sep 5 - Mon, Sep 8

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$419 Roundtrip, found 3 days ago

$419

Roundtrip

found 3 days ago

Select United flight, departing Fri, Sep 5 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $419 found 3 days ago

Fri, Sep 5 - Mon, Sep 8

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$424 Roundtrip, found 3 days ago

$424

Roundtrip

found 3 days ago

Select United flight, departing Fri, Sep 5 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $424 found 3 days ago

Fri, Sep 5 - Mon, Sep 8

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$426 Roundtrip, found 3 days ago

$426

Roundtrip

found 3 days ago

Select American Airlines flight, departing Fri, Sep 5 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $426 found 3 days ago

Fri, Sep 5 - Mon, Sep 8

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$437 Roundtrip, found 3 days ago

$437

Roundtrip

found 3 days ago

Select American Airlines flight, departing Fri, Sep 5 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $437 found 3 days ago

Mon, Sep 8 - Tue, Sep 9

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$441 Roundtrip, found 3 days ago

$441

Roundtrip

found 3 days ago

Select American Airlines flight, departing Mon, Sep 8 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Tue, Sep 9, priced at $441 found 3 days ago

Fri, Sep 5 - Mon, Sep 8

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$447 Roundtrip, found 3 days ago

$447

Roundtrip

found 3 days ago

Select Delta flight, departing Fri, Sep 5 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $447 found 3 days ago

Fri, Sep 5 - Mon, Sep 8

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$449 Roundtrip, found 3 days ago

$449

Roundtrip

found 3 days ago

Select American Airlines flight, departing Fri, Sep 5 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $449 found 3 days ago

Fri, Sep 5 - Mon, Sep 8

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$456 Roundtrip, found 3 days ago

$456

Roundtrip

found 3 days ago

Select American Airlines flight, departing Fri, Sep 5 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $456 found 3 days ago

Fri, Sep 5 - Mon, Sep 8

DTW

Detroit Metropolitan Wayne County

GSP

Greenville-Spartanburg Intl.

$457 Roundtrip, found 3 days ago

$457

Roundtrip

found 3 days ago

Select Delta flight, departing Fri, Sep 5 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Mon, Sep 8, priced at $457 found 3 days ago