Flights from Detroit to Louisville

Cheapest flights from Detroit

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Sep 11 - Thu, Sep 18

DTW

Detroit Metropolitan Wayne County

TYS

McGhee Tyson

$224 Roundtrip, found 2 days ago

$224

Roundtrip

found 2 days ago

Select Frontier Airlines flight, departing Thu, Sep 11 from Detroit Metropolitan Wayne County to McGhee Tyson, returning Thu, Sep 18, priced at $224 found 2 days ago

Thu, Sep 11 - Sun, Sep 21

DTW

Detroit Metropolitan Wayne County

TYS

McGhee Tyson

$259 Roundtrip, found 2 days ago

$259

Roundtrip

found 2 days ago

Select Frontier Airlines flight, departing Thu, Sep 11 from Detroit Metropolitan Wayne County to McGhee Tyson, returning Sun, Sep 21, priced at $259 found 2 days ago

Thu, Sep 18 - Sun, Sep 21

DTW

Detroit Metropolitan Wayne County

TYS

McGhee Tyson

$267 Roundtrip, found 2 days ago

$267

Roundtrip

found 2 days ago

Select Frontier Airlines flight, departing Thu, Sep 18 from Detroit Metropolitan Wayne County to McGhee Tyson, returning Sun, Sep 21, priced at $267 found 2 days ago

Tue, Sep 16 - Tue, Sep 23

FNT

Bishop Intl.

TYS

McGhee Tyson

$285 Roundtrip, found 2 days ago

$285

Roundtrip

found 2 days ago

Select American Airlines flight, departing Tue, Sep 16 from Bishop Intl. to McGhee Tyson, returning Tue, Sep 23, priced at $285 found 2 days ago

Mon, Sep 15 - Wed, Sep 24

FNT

Bishop Intl.

TYS

McGhee Tyson

$289 Roundtrip, found 2 days ago

$289

Roundtrip

found 2 days ago

Select American Airlines flight, departing Mon, Sep 15 from Bishop Intl. to McGhee Tyson, returning Wed, Sep 24, priced at $289 found 2 days ago

Mon, Sep 15 - Sat, Sep 20

FNT

Bishop Intl.

TYS

McGhee Tyson

$294 Roundtrip, found 2 days ago

$294

Roundtrip

found 2 days ago

Select American Airlines flight, departing Mon, Sep 15 from Bishop Intl. to McGhee Tyson, returning Sat, Sep 20, priced at $294 found 2 days ago

Sat, Sep 13 - Sat, Sep 20

FNT

Bishop Intl.

TYS

McGhee Tyson

$299 Roundtrip, found 2 days ago

$299

Roundtrip

found 2 days ago

Select American Airlines flight, departing Sat, Sep 13 from Bishop Intl. to McGhee Tyson, returning Sat, Sep 20, priced at $299 found 2 days ago

Tue, Sep 16 - Tue, Sep 23

FNT

Bishop Intl.

TYS

McGhee Tyson

$300 Roundtrip, found 2 days ago

$300

Roundtrip

found 2 days ago

Select United flight, departing Tue, Sep 16 from Bishop Intl. to McGhee Tyson, returning Tue, Sep 23, priced at $300 found 2 days ago

Tue, Sep 16 - Tue, Sep 23

FNT

Bishop Intl.

TYS

McGhee Tyson

$305 Roundtrip, found 2 days ago

$305

Roundtrip

found 2 days ago

Select United flight, departing Tue, Sep 16 from Bishop Intl. to McGhee Tyson, returning Tue, Sep 23, priced at $305 found 2 days ago

Tue, Sep 16 - Tue, Sep 23

FNT

Bishop Intl.

TYS

McGhee Tyson

$335 Roundtrip, found 2 days ago

$335

Roundtrip

found 2 days ago

Select American Airlines flight, departing Tue, Sep 16 from Bishop Intl. to McGhee Tyson, returning Tue, Sep 23, priced at $335 found 2 days ago

Tue, Sep 16 - Wed, Sep 24

FNT

Bishop Intl.

TYS

McGhee Tyson

$339 Roundtrip, found 2 days ago

$339

Roundtrip

found 2 days ago

Select American Airlines flight, departing Tue, Sep 16 from Bishop Intl. to McGhee Tyson, returning Wed, Sep 24, priced at $339 found 2 days ago

Tue, Sep 16 - Sat, Sep 20

FNT

Bishop Intl.

TYS

McGhee Tyson

$345 Roundtrip, found 2 days ago

$345

Roundtrip

found 2 days ago

Select American Airlines flight, departing Tue, Sep 16 from Bishop Intl. to McGhee Tyson, returning Sat, Sep 20, priced at $345 found 2 days ago

Wed, Sep 10 - Tue, Sep 16

DTW

Detroit Metropolitan Wayne County

TYS

McGhee Tyson

$353 Roundtrip, found 2 days ago

$353

Roundtrip

found 2 days ago

Select Delta flight, departing Wed, Sep 10 from Detroit Metropolitan Wayne County to McGhee Tyson, returning Tue, Sep 16, priced at $353 found 2 days ago

Wed, Sep 10 - Sat, Sep 20

DTW

Detroit Metropolitan Wayne County

TYS

McGhee Tyson

$356 Roundtrip, found 2 days ago

$356

Roundtrip

found 2 days ago

Select Delta flight, departing Wed, Sep 10 from Detroit Metropolitan Wayne County to McGhee Tyson, returning Sat, Sep 20, priced at $356 found 2 days ago

Mon, Sep 8 - Sat, Sep 20

DTW

Detroit Metropolitan Wayne County

TYS

McGhee Tyson

$359 Roundtrip, found 2 days ago

$359

Roundtrip

found 2 days ago

Select Delta flight, departing Mon, Sep 8 from Detroit Metropolitan Wayne County to McGhee Tyson, returning Sat, Sep 20, priced at $359 found 2 days ago

Thu, Sep 11 - Thu, Sep 18

DTW

Detroit Metropolitan Wayne County

TYS

McGhee Tyson

$361 Roundtrip, found 2 days ago

$361

Roundtrip

found 2 days ago

Select Frontier Airlines flight, departing Thu, Sep 11 from Detroit Metropolitan Wayne County to McGhee Tyson, returning Thu, Sep 18, priced at $361 found 2 days ago

Tue, Sep 16 - Tue, Sep 23

FNT

Bishop Intl.

TYS

McGhee Tyson

$365 Roundtrip, found 2 days ago

$365

Roundtrip

found 2 days ago

Select United flight, departing Tue, Sep 16 from Bishop Intl. to McGhee Tyson, returning Tue, Sep 23, priced at $365 found 2 days ago

Tue, Sep 16 - Mon, Sep 22

DTW

Detroit Metropolitan Wayne County

TYS

McGhee Tyson

$366 Roundtrip, found 2 days ago

$366

Roundtrip

found 2 days ago

Select Delta flight, departing Tue, Sep 16 from Detroit Metropolitan Wayne County to McGhee Tyson, returning Mon, Sep 22, priced at $366 found 2 days ago

Tue, Sep 16 - Tue, Sep 23

DTW

Detroit Metropolitan Wayne County

TYS

McGhee Tyson

$368 Roundtrip, found 2 days ago

$368

Roundtrip

found 2 days ago

Select American Airlines flight, departing Tue, Sep 16 from Detroit Metropolitan Wayne County to McGhee Tyson, returning Tue, Sep 23, priced at $368 found 2 days ago

Thu, Sep 11 - Thu, Sep 18

DTW

Detroit Metropolitan Wayne County

TYS

McGhee Tyson

$369 Roundtrip, found 2 days ago

$369

Roundtrip

found 2 days ago

Select Delta flight, departing Thu, Sep 11 from Detroit Metropolitan Wayne County to McGhee Tyson, returning Thu, Sep 18, priced at $369 found 2 days ago