Flights from Chicago to Central Iowa

Cheapest flights from Chicago

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$424 Roundtrip, found 2 days ago

$424

Roundtrip

found 2 days ago

Select United flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $424 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$427 Roundtrip, found 2 days ago

$427

Roundtrip

found 2 days ago

Select United flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $427 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$427 Roundtrip, found 2 days ago

$427

Roundtrip

found 2 days ago

Select American Airlines flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $427 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$434 Roundtrip, found 2 days ago

$434

Roundtrip

found 2 days ago

Select Delta flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $434 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$437 Roundtrip, found 2 days ago

$437

Roundtrip

found 2 days ago

Select American Airlines flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $437 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$447 Roundtrip, found 2 days ago

$447

Roundtrip

found 2 days ago

Select Delta flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $447 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$454 Roundtrip, found 2 days ago

$454

Roundtrip

found 2 days ago

Select United flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $454 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$457 Roundtrip, found 2 days ago

$457

Roundtrip

found 2 days ago

Select American Airlines flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $457 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$463 Roundtrip, found 2 days ago

$463

Roundtrip

found 2 days ago

Select Delta flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $463 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$467 Roundtrip, found 2 days ago

$467

Roundtrip

found 2 days ago

Select American Airlines flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $467 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$470 Roundtrip, found 2 days ago

$470

Roundtrip

found 2 days ago

Select United flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $470 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$473 Roundtrip, found 2 days ago

$473

Roundtrip

found 2 days ago

Select Delta flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $473 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$484 Roundtrip, found 2 days ago

$484

Roundtrip

found 2 days ago

Select Delta flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $484 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$487 Roundtrip, found 2 days ago

$487

Roundtrip

found 2 days ago

Select American Airlines flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $487 found 2 days ago

Sun, May 4 - Sun, May 4

ORD

O'Hare Intl.

FOD

Fort Dodge Regional

$492 Roundtrip, found 2 days ago

$492

Roundtrip

found 2 days ago

Select United flight, departing Sun, May 4 from O'Hare Intl. to Fort Dodge Regional, returning Sun, May 4, priced at $492 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$495 Roundtrip, found 2 days ago

$495

Roundtrip

found 2 days ago

Select United flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $495 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$497 Roundtrip, found 2 days ago

$497

Roundtrip

found 2 days ago

Select American Airlines flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $497 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$499 Roundtrip, found 2 days ago

$499

Roundtrip

found 2 days ago

Select United flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $499 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$502 Roundtrip, found 2 days ago

$502

Roundtrip

found 2 days ago

Select United flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $502 found 2 days ago

Mon, Oct 27 - Tue, Oct 28

ORD

O'Hare Intl.

DSM

Des Moines Intl.

$507 Roundtrip, found 2 days ago

$507

Roundtrip

found 2 days ago

Select American Airlines flight, departing Mon, Oct 27 from O'Hare Intl. to Des Moines Intl., returning Tue, Oct 28, priced at $507 found 2 days ago